Results 31 to 40 of about 1,791 (139)

Mitochondrial dysfunction-driven AMPK-p53 axis activation underpins the anti-hepatocellular carcinoma effects of sulfane sulfur [PDF]

Scientific Reports
Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, notoriously refractory to conventional chemotherapy. Historically, sulfane sulfur-based compounds have been explored for the treatment of HCC, but their efficacy has been ...
Xue Zheng, Yuhua Luo, Rui Huo, Yiwen Wang, Youbang Chen, Mianrong Chen, Qi Zhao, Kexin Li, Hanyi Zhang, Xiaotong Li, Xiang Li, Hui Zhang, Zaopeng He, Li Huang, Chun-tao Yang   +14 more
doaj   +2 more sources

Shining a light on SSP4: A comprehensive analysis and biological applications for the detection of sulfane sulfurs

Redox Biology, 2022
Fluorescent probes are useful tools for the detection of sulfane sulfurs in biological systems. In this work, we report the development of SSP4, a widely used probe generated in our laboratory.
Meg Shieh, Xiang Ni, Shi Xu, Stephen P. Lindahl, Moua Yang, Tetsuro Matsunaga, Robert Flaumenhaft, Takaaki Akaike, Ming Xian   +8 more
doaj   +3 more sources

Total sulfane sulfur bioavailability reflects ethnic and gender disparities in cardiovascular disease. [PDF]

Redox Biol, 2018
Hydrogen sulfide (H2S) has emerged as an important physiological and pathophysiological signaling molecule in the cardiovascular system influencing vascular tone, cytoprotective responses, redox reactions, vascular adaptation, and mitochondrial respiration.
Rajpal S, Katikaneni P, Deshotels M, Pardue S, Glawe J, Shen X, Akkus N, Modi K, Bhandari R, Dominic P, Reddy P, Kolluru GK, Kevil CG.   +12 more
europepmc   +4 more sources

Synechococcus sp. PCC7002 Uses Peroxiredoxin to Cope with Reactive Sulfur Species Stress

mBio, 2022
Cyanobacteria are a widely distributed group of microorganisms in the ocean, and they often need to cope with the stress of reactive sulfur species, such as sulfide and sulfane sulfur.
Daixi Liu, Jinyu Chen, Yafei Wang, Yue Meng, Yuanning Li, Ranran Huang, Yongzhen Xia, Huaiwei Liu, Nianzhi Jiao, Luying Xun, Jihua Liu   +10 more
doaj   +1 more source

New fluorescent probes for sulfane sulfurs and the application in bioimaging [PDF]

Chemical Science, 2013
A sulfane sulfur mediated benzodithiolone formation was developed. Based on this reaction, two fluorescent probes (SSP1 and SSP2) for the detection of sulfane sulfur species (persulfide, polysulfide, and elemental sulfur) were prepared and evaluated. The probes showed high selectivity and sensitivity to sulfane sulfurs.
Chen, Wei, Liu, Chunrong, Peng, Bo, Zhao, Yu, Pacheco, Armando, Xian, Ming   +5 more
openaire   +3 more sources

Isotope dilution mass spectrometry for the quantification of sulfane sulfurs [PDF]

Free Radical Biology and Medicine, 2014
Sulfane sulfurs are one type of important reactive sulfur species. These molecules have unique reactivity that allows them to attach reversibly to other sulfur atoms and exhibit regulatory effects in diverse biological systems. Recent studies have suggested that sulfane sulfurs are involved in signal transduction processes regulated by hydrogen sulfide
Liu, Chunrong, Zhang, Faya, Munske, Gerhard, Zhang, Hui, Xian, Ming   +4 more
openaire   +3 more sources

The multifaceted roles of sulfane sulfur species in cancer-associated processes

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2021
Sulfane sulfur species comprise a variety of biologically relevant hydrogen sulfide (H2S)-derived species, including per- and poly-sulfidated low molecular weight compounds and proteins. A growing body of evidence suggests that H2S, currently recognized as a key signaling molecule in human physiology and pathophysiology, plays an important role in ...
Zuhra, Karim, Tomé, Catarina S, Forte, Elena, Vicente, João B, Giuffrè, Alessandro   +4 more
openaire   +4 more sources

Intranasal administration of polysulfide prevents neurodegeneration in spinal cord and rescues mice from delayed paraplegia after spinal cord ischemia

Redox Biology, 2023
Background: Delayed paraplegia is a devastating complication of thoracoabdominal aortic surgery. Hydrogen sulfide (H2S) was reported to be protective in a mouse model of spinal cord ischemia and the beneficial effect of H2S has been attributed to ...
Eiki Kanemaru, Yusuke Miyazaki, Eizo Marutani, Mariko Ezaka, Shunsaku Goto, Etsuo Ohshima, Donald B. Bloch, Fumito Ichinose   +7 more
doaj   +1 more source

Sulfane Sulfur Compounds as Source of Reappearance of Reductive Off-Odors in Wine

Fermentation, 2022
Reactive compounds with one or more sulfane sulfur atoms can be an important source of reductive off-odors in wine. These substances contain labile sulfur, which can participate in microbiological (enzymatic) and chemical transformations (including in ...
Nikolaus Müller, Doris Rauhut, Andrii Tarasov   +2 more
doaj   +1 more source

Sulfane sulfur – new findings on an old topic

Acta Biochimica Polonica, 2019
Sulfane sulfur is a divalent sulfur atom bonded to another sulfur which is very reactive and labile. Compounds containing this reactive sulfur include persulfides, polysulfides, thiosulfate, thiosulfinates, polythionates, and elemental sulfur. Sulfane sulfur appears in a number of biologically important compounds, including thiocysteine, thiocystine ...
Malgorzata Iciek, Anna Bilska-Wilkosz, Magdalena Górny   +2 more
openaire   +4 more sources