Results 21 to 30 of about 1,072 (172)
Amino acids as selective acylating agents: regioselective N-1-acylation of imidazolidin-4-one derivatives of the antimalarial drug primaquine [PDF]
, 2008 The acylation of bioactive primaquine-based imidazolidin-4-ones was studied using N-chi-Boc-protected glycine as acylating agent. Two synthesis routes, eight different coupling methods and seven distinct solvents were compared.
Joana Matos +3 more
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Безопасность и риск фармакотерапии, 2019 EEosinophilia can be caused by various reasons, including taking certain medications, in which case it is called drug-induced. The relevance of drug-induced eosinophilia issue is due to the serious consequences associated with this condition, in ...
O. D. Ostroumova +2 more
doaj +1 more source
Gas-phase acidity of sulfonamides: implications for reactivity and prodrug design [PDF]
, 2005 A computational study at the density functional theory level was performed on bioactive and model sulfonamides with the aim of determining the factors affecting the acidity of the sulfonamido group.
Gomes, JRB, Gomes, P
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BMC Plant Biology, 2012 Background The sulfanilamide family comprises a clinically important group of antimicrobial compounds which also display bioactivity in plants. While there is evidence that sulfanilamides inhibit folate biosynthesis in both bacteria and plants, the ...
Schreiber Karl J +7 more
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A Case of Multiple Antibiotic-Associated Hepatotoxicity in an Infant
Безопасность и риск фармакотерапии, 2019 Drug induced liver injury is one of the most frequent reasons for stopping treatment and the main cause of the onset and progression of acute liver failure, requiring liver transplantation.
S. S. Postnikov +7 more
doaj +1 more source
Synthesis and Characterization of Azo Dye Para Red and New Derivatives [PDF]
, 2012 Azo dyes para red was synthesized. The products were characterized by FTIR and UV-Visible spectrophotometers.
L. Abd-Alredha R. Al-Rubaie +1 more
core +5 more sources
Paradigm of modern pharmacology: development and current approaches [PDF]
, 2016 The article focuses on the current approach to understanding pharmaceutical products’ effect. It describes a paradigm shift in views on pharmaceutical action in correlation to the processes occurring under pathology.
Reznikov, K. M.
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Applied Computational Techniques on Schizophrenia Using Genetic Mutations [PDF]
, 2013 [Abstract] Schizophrenia is a complex disease, with both genetic and environmental influence. Machine learning techniques can be used to associate different genetic variations at different genes with a (schizophrenic or non-schizophrenic) phenotype ...
Aguiar-Pulido, Vanessa +4 more
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Antibacterial and cytotoxic activity of metronidazole and levofloxacin composites with silver nanoparticle [PDF]
, 2021 The aim of the work is to to ascertain their antibacterial activity, as well as the toxic effects toward human cells of composites of silver nanoparticles immobilized by electron-beam technology onto crystals of antimicrobial agents metronidazole and ...
Bilous, Svitlana +13 more
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Determination of Microbial Susceptibility to Sulfanilamides by Electrooptic Analysis
Антибиотики и Химиотерапия, 2020 The effect of sulfanilamides (soluble streptocid as an example) on changing of the electrophysical properties (EP) of microbial cells of Escherichia coli XL-1, BL-Ril, Pseudomonas putida C-11 and BA-11 was studied.
O. I. Guliy +4 more
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