Results 31 to 40 of about 784 (187)

Problems of in vitro Antibiotic Susceptibility Compliance with Efficacy of Chemotherapy in Infections Due to Pathogenic Burkholderias

open access: yesАнтибиотики и Химиотерапия, 2020
Among the known species of Burkholderia only two are obligate pathogens, i. e. B.mallei and B.pseudomallei, causative agents of glanders and melioidosis respectively.
V. I. Ilyukhin   +5 more
doaj  

Ecotoxicological Insights From Ex Vivo Exposure of Whole Blood to PFOS and Glyphosate: Oxidative Stress and Immune Disruption

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT This study investigated the immunomodulatory effects of PFOS and glyphosate (GLY), both individually and in combination, on the whole blood of three ruminant species (cow, goats, and sheep) exposed ex vivo to environmentally relevant concentrations. The research focused on key biomarkers of oxidative stress (MDA), inflammation (myeloperoxidase
Francesco Molinari   +8 more
wiley   +1 more source

Maternal Lead Exposure Induces Glandular Alterations in the Salivary Glands of Rat Male Offspring

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Lead (Pb) is a widely distributed environmental pollutant that is highly noxious due to its toxicokinetic characteristics. Pb exposure can damage vital organ systems, including the central nervous and stomatognathic systems. As salivary glands play an important role in oral homeostasis, this study aimed to investigate the effects of maternal ...
Rayssa Maitê Farias Nazário   +8 more
wiley   +1 more source

Antibacterial efect of some new organic compounds of sulfanilamides range [PDF]

open access: yes, 2009
Laboratorul „Infecţii intraspitaliceşti” USMF „NicolaeTestemiţanu” Catedra chimie anorganică şi fizică USMThis study is refering to a new organic compounds of sulfanilamides range, which shows higher antibacterial activity to grampositive and ...
Ţapcov, Victor   +3 more
core  

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants

open access: yesThe FEBS Journal, EarlyView.
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet   +6 more
wiley   +1 more source

PbrIDD2‐PbrAPX14 Module Functions in the Ethylene‐Mediated Ripening and Senescence Process of Pear Fruit

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Endogenous H2O2 participated in the ethylene‐dependent ripening and senescence process of horticultural fruit as a secondary messenger; however, the molecular mechanism beneath such a phenomenon has not been fully clarified until recently. By a conjoint analysis of metabolite, enzyme activities, gene expression profiles in AsA‐GSH cycle of ...
Libin Wang   +12 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

In Silico Assessment of Enaminone–Sulfanilamides as Potential Carbonic Anhydrase II Inhibitors: Molecular Docking and ADMET Prediction

open access: yesChemistry Proceedings
Carbonic anhydrases (CAs) are a group of zinc-containing enzymes involved in many physiological processes through their role in the maintenance of the equilibrium between bicarbonate and CO2 levels.
Yousra Ouafa Bouone   +3 more
doaj   +1 more source

A framework for using tissue chemistry and biochronologies to reconstruct fish habitat use and growth

open access: yesEcological Solutions and Evidence, Volume 7, Issue 3, July–September 2026.
Caption to use for Graphical Abstract (if caption not provided with separate file): A novel and accessible framework for using chemical tracers in fish tissues for addressing ecological questions, with a primary focus on habitat use and movement reconstruction.
Peter Betts   +6 more
wiley   +1 more source

Nebivolol Protects the Thoracic and Abdominal Aorta and Their Perivascular Adipose Tissue From the Differential Detrimental Effects of Obesity

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 4, July 2026.
ABSTRACT The effects of obesity on the vasculature and perivascular adipose tissue (PVAT) function vary according to the vascular territory. Nebivolol is a third‐generation β‐blocker that exerts vasculoprotective effects in obesity. The thoracic and abdominal aorta show different responses under physiological conditions, and their PVATs have a ...
Thales M. H. Dourado   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy