Short SULF1/SULF2 splice variants predominate in mammary tumours with a potential to facilitate receptor tyrosine kinase-mediated cell signalling [PDF]
, 2016 The relative roles of SULF1 and SULF2 enzymes in tumour growth are controversial, but short SULF1/SULF2 splice variants predominate in human mammary tumours despite their non-detectable levels in normal mammary tissue. Compared with the normal, the level
Dhoot, G K +3 more
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Researches on Sulfatase Models, IV
NIPPON KAGAKU KAISHI, 1939 unsym.メチルフェニルヒドラヂンはヒドラヂン以上にグルコーゼ硫酸の分解を促進するが, Sym.アセチルフェニルヒドラヂンは全くその作用がない.從つてグルコスルフ,ターゼ模型としての作用を有する爲にはヒドラヂンの少くとも1個のアミノ基は遊離して居なければならないと思はれる.グルコスルファターゼ模型としてのヒドラヂンの特異性は必ずしもグルコスルファターゼの特異性と現在見做されて居るもの2)とは一致しない.即ち,バウシウボラより得られたグルコスルファターゼ製品はα-メチルグルコシド硫酸,蔗糖硫酸等をも分解するが,ヒドラヂンは,ヒドラヂン誘導體縮合生成物を作る様な還元糖等の硫酸エステルに限り分解する.
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Riding the sulfur cycle - metabolism of sulfonates and sulfate esters in Gram-negative bacteria [PDF]
, 2017 Sulfonates and sulfate esters are widespread in nature, and make up over 95% of the sulfur content of most aerobic soils. Many microorganisms can use sulfonates and sulfate esters as a source of sulfur for growth, even when they are unable to metabolize ...
Kertesz, Michael A.
core
Molecular Genetics and Metabolism Reports, 2018 Mucopolysaccharidosis (MPS) is a genetic disorder characterized by the accumulation of glycosaminoglycans in the body. Of the multiple MPS disease subtypes, several are caused by defects in sulfatases.
Ryuichi Mashima +3 more
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Differential Sulfation Remodelling of Heparan Sulfate by Extracellular 6-O-Sulfatases Regulates Fibroblast Growth Factor-Induced Boundary Formation by Glial Cells: Implications for Glial Cell Transplantation [PDF]
, 2012 Jennifer R. Higginson +5 more
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Determination of Rottlerin, a Natural Protein Kinases C Inhibitor, in Pancreatic Cancer Cells and Mouse Xenografts by RP-HPLC Method. [PDF]
, 2013 Rottlerin is a natural polyphenolic ketone isolated from the pericarps of Mallotus phillippinensis. In previous studies we showed that parenteral administration of rottlerin reduced tumor growth in murine xenograft models of pancreatic cancer. The aim of
Edderkaoui, Mouad +7 more
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Cell Reports, 2018 Summary: Multiple sulfatase deficiency (MSD) is a fatal, inherited lysosomal storage disorder characterized by reduced activities of all sulfatases in patients.
Lars Schlotawa +6 more
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A novel iPSC model reveals selective vulnerability of neurons in multiple sulfatase deficiency [PDF]
, 2023 Vi Pham +14 more
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Steroid Sulfatase: A New Target for the Endocrine Therapy of Breast Cancer [PDF]
, 2007 Susannah Stanway +6 more
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Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 Ring A halogenated 13α-, 13β-, and 17-deoxy-13α-estrone derivatives were synthesised with N-halosuccinimides as electrophile triggers. Substitutions occurred at positions C-2 and/or C-4.
Ildikó Bacsa +10 more
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