Results 241 to 250 of about 31,137 (305)

Advances in mucopolysaccharidosis research: the impact of mass spectrometry-based approaches. [PDF]

Clin Proteomics
Ramarajan MG, Garapati K, Ghose V, Pandey A.   +3 more
europepmc   +1 more source

Sulfatase modifying factor 2 as a predictive biomarker for urothelial carcinoma. [PDF]

Discov Oncol
Kuo WT, Lee YC, Liao JB, Tseng CJ, Yang YF.   +4 more
europepmc   +1 more source

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Sulfatase-Induced In Situ Formulation of Antineoplastic Supra-PROTACs

Journal of the American Chemical Society
Proteolysis targeting chimera (PROTAC) technology is an innovative strategy for cancer therapy, which, however, suffers from poor targeting delivery and limited capability for protein of interest (POI) degradation.
Peng Zhang, Zhonghua Liu, Zhilin Yu
exaly   +2 more sources

Activatable Near-Infrared Fluorescent and Photoacoustic Dual-Modal Probe for Highly Sensitive Imaging of Sulfatase In Vivo.

ACS Sensors, 2023
Sulfatase is an important biomarker closely associated with various diseases. However, the state-of-the-art sulfatase probes are plagued with a short absorption/emission wavelength and limited sensitivity.
Mei-Hao Xiang, Zhiyong Jiang, Wenting Zhao, Ensheng Zhang, Lian Xia, Rongmei Kong, Yan Zhao, Weiheng Kong, Xianjun Liu, Fengli Qu, Weihong Tan   +10 more
semanticscholar   +1 more source

Residual Host Cell Protein Promotes Polysorbate 20 Degradation in a Sulfatase Drug Product Leading to Free Fatty Acid Particles

Journal of Pharmaceutical Sciences, 2016
N. Dixit, Nazila Salamat-Miller, P. Salinas, Katherine D Taylor, S. Basu   +4 more
exaly   +2 more sources

Glucosinolate Sulfatases-Sulfatase-Modifying Factors System Enables a Crucifer-Specialized Moth To Pre-detoxify Defensive Glucosinolate of the Host Plant.

Journal of Agricultural and Food Chemistry, 2022
Numerous herbivores orally secrete defense compounds to detoxify plant toxins. However, little is known about the role of orally secreted enzymes by a specialized pest, Plutella xylostella, in the detoxification of plant defense compounds.
Wei Chen, H. S. A. Saqib, Xuejiao Xu, Yuhong Dong, Ling Zheng, Ying-Jang Lai, Xiaodong Jing, Zhanjun Lu, Linyang Sun, M. You, Weiyi He   +10 more
semanticscholar   +1 more source

Steroid sulfatase inhibitors: the current landscape

Expert Opinion on Therapeutic Patents, 2021
Introduction: Steroid sulfatase (STS) enzyme is responsible for transforming the inactive sulfate metabolites of steroid sex hormones into the active free steroids.
Hanan S. Anbar, Z. Isa, Jana J Elounais, Mariam A Jameel, Judy Hussam, Aya M Samer, Aya F Jawad, M. El‐Gamal   +7 more
semanticscholar   +1 more source