Results 31 to 40 of about 5,662 (212)
Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship [PDF]
Human Molecular Genetics, 2005 Sulfatases catalyze the hydrolysis of sulfate ester bonds from a wide variety of substrates. Several human inherited diseases are caused by the deficiency of individual sulfatases, while in patients with multiple sulfatase deficiency mutations in the Sulfatase Modifying Factor 1 (SUMF1) gene cause a defect in the post-translational modification of a ...
SARDIELLO M. +3 more
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Expression and Role of Heparan Sulfated Proteoglycans in Pancreatic Cancer
Frontiers in Oncology, 2021 Pancreatic cancer is a lethal condition with poor outcomes and an increasing incidence. The unfavourable prognosis is due to the lack of early symptoms and consequent late diagnosis.
Simone Furini, Chiara Falciani
doaj +1 more source
SUMF1 enhances sulfatase activitiesin vivoin five sulfatase deficiencies [PDF]
Biochemical Journal, 2007 Sulfatases are enzymes that hydrolyse a diverse range of sulfate esters. Deficiency of lysosomal sulfatases leads to human diseases characterized by the accumulation of either GAGs (glycosaminoglycans) or sulfolipids. The catalytic activity of sulfatases resides in a unique formylglycine residue in their active site generated by the post-translational ...
FRALDI, ALESSANDRO +10 more
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Balanços metabólicos do enxofre em pacientes com leucodistrofia metacromática
Arquivos de Neuro-Psiquiatria, 1968 Foram estudados os balanços metabólicos do enxofre em dois pacientes com a forma juvenil da leucodistrofia metacromática. Foi verificado, em ambos os casos, um balanço positivo desse metaloide, aparentemente não influenciado pelo tipo de dieta (geral ou ...
Horacio M. Canelas +2 more
doaj +1 more source
JIMD Reports, 2019 Multiple sulfatase deficiency (MSD) is an ultra‐rare lysosomal storage disorder (LSD). Mutations in the SUMF1 gene encoding the formylglycine generating enzyme (FGE) result in an unstable FGE protein with reduced enzymatic activity, thereby affecting the
Lars Schlotawa +6 more
doaj +1 more source
Frontiers in Plant Science, 2015 Many algae are rich sources of sulfated polysaccharides with biological activities. The physicochemical/rheological properties and biological activities of sulfated polysaccharides are affected by the pattern and number of sulfate moieties.
Chai-Ling eHo
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Proteoglycan desulfation: a critical step in oncogenesis?
Frontiers in Bioscience-Landmark, 2020 Proteoglycans are essential constituents of tissue- and organ microenvironments, modulating both the structural scaffolds that surround cells as well as signaling cues that determine cellular phenotype.
Vishal Singh, Ramray Bhat
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CO2 Fluxes and Soil Responses to Straw and Herbicide in Peanut
Land Degradation &Development, EarlyView.ABSTRACT Peanut cultivation plays an important agronomic role in Brazil, especially in rotation with sugarcane, promoting biological nitrogen fixation and improving soil quality. This study aimed to test the hypothesis that the combined use of sugarcane mulch, peanut cultivation, and herbicide application would affect soil CO₂ fluxes, soil chemical ...
Heytor Lemos Martins +7 more
wiley +1 more source
Purple Urine Bag Syndrome [PDF]
Journal of Clinical and Diagnostic Research, 2015 Purple urine bag syndrome (PUBS) is a rare disorder seen in elderly persons, wherein the urinary bag and the tubing turn in to purple colour. It is usually seen in patients who are on urinary catheters for a long time.
NAUFAL RIZWAN TARAGANAR ABUBACKER +4 more
doaj +1 more source
Síndrome de la bolsa de orina púrpura
Atención Primaria Práctica, 2022 Resumen: Se presenta el caso de un paciente con incontinencia urinaria de urgencia por hemiplejía, que acude a consulta por fiebre y malestar general; llama la atención que trae una bolsa recolectora de coloración púrpura.
Juan Sebastian Theran León +3 more
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