Results 61 to 70 of about 5,662 (212)

Research and Application of Chondroitin Sulfate/Dermatan Sulfate-Degrading Enzymes

open access: yesFrontiers in Cell and Developmental Biology, 2020
Chondroitin sulfate (CS) and dermatan sulfate (DS) are widely distributed on the cell surface and in the extracellular matrix in the form of proteoglycan, where they participate in various biological processes.
Wenshuang Wang   +3 more
doaj   +1 more source

Enhanced below‐ground functioning is associated with higher plant resistance against drought: Implications for ecosystem functions

open access: yesJournal of Ecology, Volume 114, Issue 3, March 2026.
The results suggest that the subordinate species achieves higher drought resistance in biomass and soil functions via increased below‐ground functioning. The data presented here provide a basis to explain the underlying mechanisms behind the response of grassland communities and their C cycling to drought.
Alberto Canarini   +12 more
wiley   +1 more source

Structural Basis of Mucopolysaccharidosis Type II and Construction of a Database of Mutant Iduronate 2-Sulfatases. [PDF]

open access: yesPLoS ONE, 2016
Mucopolysaccharidosis type II (MPS II, Hunter syndrome) is an X-linked genetic disorder caused by a deficiency of iduronate 2-sulfatase (IDS), and missense mutations comprising about 30% of the mutations responsible for MPS II result in heterogeneous ...
Seiji Saito   +3 more
doaj   +1 more source

Epidemiology of progressive intellectual and neurological deterioration in UK children

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 3, Page 418-428, March 2026.
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity   +3 more
wiley   +1 more source

Iduronate 2-Sulfatase [PDF]

open access: hybrid, 2020
National Cancer Institute
openalex   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

open access: yesTraffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang   +7 more
wiley   +1 more source

Genetic Heterogeneity of Iduronate-2-Sulfatase in Children Diagnosed with Mucopolysaccharidosis Type II in Azerbaijan [PDF]

open access: bronze, 2023
Alizada Sevda Aydin   +4 more
openalex   +1 more source

Bisphenol B Exposure Induces Miscarriage by Suppressing Migration/Invasion and Migrasome Formation

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
BPB (Bisphenol B) exposure up‐regulates ER (estrogen receptor) levels, enhances its interactions with the lnc‐HZ04 promoter region, and thus promotes ER‐mediated lnc‐HZ04 transcription. Subsequently, lnc‐HZ04 suppresses TCF4 (transcription factor 4)‐mediated PKCA (protein kinase C alpha) transcription and subsequently suppresses migration/invasion and ...
Wenxin Huang   +13 more
wiley   +1 more source

Elucidation of Proteoforms of Chinese Hamster Ovary (CHO) Phospholipase B‐Like 2 (PLBL2) Captured From a Monoclonal Antibody

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 2, Page 406-419, February 2026.
A platform approach to the affinity capture and enrichment of host cell proteins to enable their subsequent deep characterization and elucidation of variants or proteoforms (e.g., molecular size variants, charge variants, glycoforms, etc.). ABSTRACT Removing host cell proteins (HCPs) during biotherapeutic manufacturing is essential to ensure patient ...
Michael E. Dolan   +6 more
wiley   +1 more source

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