Lead as a tracer for automotive particulates: projecting the sulfate air quality impact of oxidation catalyst-equipped cars in Los Angeles [PDF]
An analysis of the fate of lead in the Los Angeles Basin is used to evaluate an emissions to air quality model for automotive exhaust particulates. The dispersion model is then applied to projecting the annual average sulfate air quality impact of direct
Cass, Glen R.
core
Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome
ABSTRACT Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels. Methods Patients with FIRES admitted to the Intensive Care Unit (ICU) of Beijing Children's Hospital were retrospectively ...
Yushan He+7 more
wiley +1 more source
Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function. [PDF]
The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood.
Chen, Jihuan+9 more
core +1 more source
Dimethyl sulfate and diisopropyl sulfate as practical and versatile O-sulfation reagents
AbstractO-Sulfation is a vital post-translational modification in bioactive molecules, yet there are significant challenges with their synthesis. Dialkyl sulfates, such as dimethyl sulfate and diisopropyl sulfate are commonly used as alkylation agents in alkaline conditions, and result in the formation of sulfate byproducts.
Shuaishuai Yue+6 more
openaire +3 more sources
Indoxyl Sulfate—Review of Toxicity and Therapeutic Strategies
Indoxyl sulfate is an extensively studied uremic solute. It is a small molecule that is more than 90% bound to plasma proteins. Indoxyl sulfate is derived from the breakdown of tryptophan by colon microbes.
Sheldon C. Leong, T. Sirich
semanticscholar +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source
Expanding Use of Magnesium Sulfate for Treatment of Pre-eclampsia and Eclampsia [PDF]
Pre-eclampsia/eclampsia is a serious condition that can develop during pregnancy, even in women with no risk factors. Although there is little understanding of what causes pre-eclampsia/eclampsia, there is an effective treatment for this condition which,
Elisa Wells+3 more
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Adenosine-5′-phosphosulfate - a multifaceted modulator of bifunctional 3′-phospho-adenosine-5′-phosphosulfate synthases and related enzymes [PDF]
All sulfation reactions rely on active sulfate in the form of 3′-phosphoadenosine-5′-phosphosulfate (PAPS). In fungi, bacteria, and plants, the enzymes responsible for PAPS synthesis, ATP sulfurylase and adenosine-5′-phosphosulfate (APS) kinase, reside ...
Allali-Hassani+46 more
core +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim+3 more
wiley +1 more source
Anthropogenic signals recorded in an ice core from Eclipse Icefield, Yukon Territory, Canada [PDF]
Trends in the annual flux of sulfate and nitrate in a new ice core collected at an elevation of 3017 m on Eclipse Icefield, 45 km northeast of Mt. Logan were examined to determine the effect of anthropogenic activity on precipitation chemistry in the ...
Wake, Cameron P, Yalcin, Kaplan
core +3 more sources