Results 51 to 60 of about 887,382 (298)
Frontiers in Microbiology, 2017 Metals play an important role in microbial metabolism by acting as cofactors for many enzymes. Supplementation of biological processes with metals may result in improved performance, but high metal concentrations are often toxic to microorganisms.
Lara M. Paulo +5 more
doaj +1 more source
Orthogonal Sulfation Strategy for Synthetic Heparan Sulfate Ligands. [PDF]
ChemInform, 2005 [reaction: see text] An orthogonal sulfation strategy involving six different protecting groups has been developed for generating sulfated carbohydrate libraries based on heparan. Chemoselective cleavage conditions (optimized for a heparan disaccharide) can be performed in the presence of sulfate esters as well as the remaining protecting groups.
Ren-Hua, Fan +3 more
openaire +3 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Sulfate-reducing bacteria of the human intestine. I. Dissimilatory sulfate reduction
Біологічні студії, 2012 Modern literature data concerning sulfate-reducing bacteria of human intestine are summarized. The characterictics and mechanisms of dissimilatory sulfate reduction by these bacteria are described.
I. V. Kushkevych
doaj +1 more source
Estuary Sediment Treatment for Reducing Sulfate in Acid Mine Water
Environment and Natural Resources Journal, 2020 Acid mine water causes environmental problems due to its high acidity caused by its high sulfate content which can disturb the life of organisms. This problem can be resolved by utilizing sulfate-reducing bacteria (SRB) abundantly found in sediments ...
Fahruddin Fahruddin +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Determination of sulfate in the wet-process of phosphoric acid by reverse flow injection
Química Nova, 2014 An improved method based on reverse flow injection is proposed for determining sulfate concentration in the wet-process of phosphoric acid (WPA). The effect of reagent composition, flow rate, temperature, acid concentration, length of the reaction coil ...
Wenhui Shi +4 more
doaj +1 more source
Investigating the effects of novel heparan sulfate mimetic 'HS16-35' on immune cell migration in an in vitro model of the blood-CSF barrier. [PDF]
, 2021 Maddie Griffiths
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source