Results 61 to 70 of about 1,022,238 (313)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Biotechnological aspects of anaerobic oxidation of methane coupled to sulfate reduction [PDF]
, 2009 Sulfate reduction (SR) can be used for the removal and recovery of metals and oxidized sulfur compounds from waste streams. Sulfate-reducing bacteria reduce oxidized sulfur compounds to sulfide.
Meulepas, R.J.W.
core
Scientific ReportsA geopolymer (GP) from Partially Dealuminated Kaolin (PDK) was synthesized. PDK is a solid waste of alum industry, it was produced in a big quantity, which need careful management to be recycled for protection of the environment against pollution ...
Khaled Elewa +4 more
doaj +1 more source
Biology, 2013 Fimbriae are long, proteinaceous adhesion organelles expressed on the bacterial envelope, evolutionarily adapted by Escherichia coli strains for the colonization of epithelial linings. Using glycan arrays of the Consortium for Functional Glycomics (CFG),
Manfred Wuhrer +11 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Characterization of PmHS2 glycosyltransferases for the controlled synthesis of heparosan : a precursor of heparin and heparan sulfate [PDF]
, 2011 Heparin (Hep), a highly sulfated and complex glycosaminoglycan polysaccharides, is worldwide used as an anticoagulant compound to prevent blood clotting during surgery.
Chavaroche, A.A.E.
core
The role of electron donor in simultaneous degradation of 2,4,6-trichlorophenol and sulfate
上海师范大学学报. 自然科学版, 2020 It is common that industrial wastewater contains 2,4,6-trichlorophenol(TCP) and sulfate simultaneously.Biological reduction is an effective method to remove the pollutants in the wastewater simultaneously.Pyruvic acid was used as an external electron ...
SUN Lizhu, SHEN Yong, WANG Chengqi
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
MicroorganismsSulfide is a toxic and hazardous substance in the agricultural environment, which can cause damage to humans and livestock when exposed to large amounts of air.
Xuechun Wang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source