Results 51 to 60 of about 823,047 (268)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Association between intravenous magnesium sulfate and mortality in patients with sepsis-associated liver injury: a retrospective cohort study

Frontiers in Medicine
BackgroundSepsis-associated liver injury (SALI) is a significant risk factor for mortality in patients with sepsis. Magnesium, as an essential electrolyte, has a correlation with adverse outcomes in critical illness when deficient, yet the therapeutic ...
Chen Ouyang, Yuxi Liu, Xin Li, Pengpeng Liu, Quanyan Liu   +4 more
doaj   +1 more source

Crystal Structures of Two 1,4-Diamino-1,2,4-triazolium Salts

Crystals, 2016
Bis(1,4-diamino-1,2,4-triazolium) sulfate (1) was obtained from the corresponding chloride by ion metathesis using Ag2SO4. Further metathesis with barium 5,5′-azotetrazolate yielded bis(1,4-diamino-1,2,4-triazolium) 5,5′-azotetrazolate (2). Numerous NH···
Gerhard Laus, Klaus Wurst, Volker Kahlenberg, Herwig Schottenberger   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Fontes e doses de potássio na produção e qualidade do grão de café beneficiado Sources and doses of potassium on the yield and quality of green coffee

Pesquisa Agropecuária Brasileira, 1999
Um experimento de campo foi instalado num Latossolo Roxo distrófico, localizado na Fazenda Experimental da EPAMIG, São Sebastião do Paraíso, MG, em fevereiro de 1993, utilizando-se a espécie Coffea arabica L., cultivar Catuaí Vermelho, linhagem LCH 2077 ...
Enilson de Barros Silva, Francisco Dias Nogueira, Paulo Tácito Gontijo Guimarães, Silvio Júlio de Rezende Chagas, Laerte Costa   +4 more
doaj   +1 more source

Liberation of sulfate from sulfate esters by soils [PDF]

Applied and Environmental Microbiology, 1976
When incubated with acid, alkaline, and neutral soils, a variety of synthetic sulfate esters representing the various classes of these compounds was hydrolyzed by enzymes, probably of microbial origin. The appearance of sulfate in the soil water occurred immediately after introduction into the soils with some esters, whereas with others it occurred ...
C, Houghton, R A, Rose
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Methane reductions with gypsum and SOP® lagoon additives in liquid manure

Frontiers in Climate
The agriculture industry is an important source of greenhouse gas emissions globally with livestock production being a main contributor. Therefore, there is a need to reduce methane (CH4) emissions from livestock production, including liquid manure ...
Chelsea Sauvé, Chelsea Sauvé, Hambaliou Baldé, Rajinikanth Rajagopal, Andrew VanderZaag   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Electrodeposition of Copper–Nickel Foams: From Separate Phases to Solid Solution

Crystals
Copper-based electrocatalytic materials with high surface area are essential for various processes, such as water splitting and the electroreduction of carbon dioxide and nitrates.
Eduard E. Levin, Victoria P. Chertkova, Natalia A. Arkharova   +2 more
doaj   +1 more source