Results 101 to 110 of about 715,652 (297)

Effect of intrauterine morphine sulfate exposure on cerebellar histomorphological changes in neonatal mice [PDF]

, 2011
Neurotoxic effects of morphine sulfate in adult cerebellar cortex and neonatal cerebral cortex have been studied in animal models. This study was done to determine the neurotoxic effects of prenatal morphine exposure on the histo morphological changes of
Ghafari, S., Golalipour, M.J., Roshandel, D.   +2 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Anaerobic Oxidation of Ethane, Propane, and Butane by Marine Microbes: A Mini Review

Frontiers in Microbiology, 2017
The deep ocean and its sediments are a continuous source of non-methane short-chain alkanes (SCAs) including ethane, propane, and butane. Their high global warming potential, and contribution to local carbon and sulfur budgets has drawn significant ...
Rajesh Singh, Michael S. Guzman, Arpita Bose   +2 more
doaj   +1 more source

Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e [PDF]

, 2016
Engineered nanoparticles are becoming increasingly incorporated into technology and consumer products. In 2014, over 300 tons of copper oxide nanoparticles were manufactured in the United States.
Andersen, Erik C., Hristova, Krassimira R., Kappell, Anthony D., Mashock, Michael Joseph, Petrella, Lisa N., Zanon, Tyler   +5 more
core   +1 more source

Phosphorus and arsenic distributions in a seasonally-stratified, iron- and manganese-rich lake: microbiological and geochemical controls [PDF]

, 2015
Seasonal stratification in temperate lakes greater than a few metres deep provides conditions amenable to pronounced vertical zonation of redox chemistry.
Anderson, Martin S., Hamilton, David P., Hartland, Adam   +2 more
core   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Key microbial functional genes and their diversity involved in soil typical reduction processes: A review

浙江大学学报. 农业与生命科学版, 2017
Soil is a complex redox system where many active biogeochemical processes co- occurred, such as denitrification, iron/sulfate reduction, methanogenesis and reductive dehalogenation, etc.
FENG Jiayin, ZHU Min, HE Yan
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

High-Quality Draft Genome Sequence of Desulfovibrio carbinoliphilus FW-101-2B, an Organic Acid-Oxidizing Sulfate-Reducing Bacterium Isolated from Uranium(VI)-Contaminated Groundwater. [PDF]

, 2015
Desulfovibrio carbinoliphilus subsp. oakridgensis FW-101-2B is an anaerobic, organic acid/alcohol-oxidizing, sulfate-reducing δ-proteobacterium. FW-101-2B was isolated from contaminated groundwater at The Field Research Center at Oak Ridge National Lab ...
Arkin, Adam P, Carroll, Sue L, Chakraborty, Romy, Cheng, Jan-Fang, Chertkov, Olga, Chivian, Dylan, Criddle, Craig S, Dehal, Paramvir, Detter, John C, Fields, Matthew W, Goodwin, Lynne A, Han, Cliff S, Han, James, Hauser, Loren J, Hazen, Terry C, Held, Brittany, Hwang, Chiachi, Ivanova, Natalia N, Kyrpides, Nikos C, Land, Miriam L, Lapidus, Alla L, Lucas, Susan, Mikhailova, Natalia, Pagani, Ioanna, Peters, Lin, Pitluck, Samuel, Ramsay, Bradley D, Tapia, Roxanne, Woo, Hannah L, Woyke, Tanja, Wu, Weimin   +30 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source