Results 141 to 150 of about 402,020 (174)

A new sulfated β-galactan from clams with anti-HIV activity

Carbohydrate Research, 1999
A new polysaccharide composed of galactan sulfate with a beta-(1-->3)-glycosidic linkage has been isolated from the marine clam species Meretrix petechialis. The polysaccharide was homogeneous in its composition containing D-galactose. The glycosidic linkage was examined by 2D DQF-COSY and 2D NOESY spectroscopy. The coupling constant of anomeric proton
C, Amornrut, T, Toida, T, Imanari, E R, Woo, H, Park, R, Linhardt, S J, Wu, Y S, Kim   +7 more
openaire   +2 more sources

ANALYSIS OF Botryocladia occidentalis (RHODOPHYTA) SULFATED GALACTANS AS MODULATORS OF THROMBIN GENERATION

Revista Brasileira de Engenharia de Pesca
The cell-wall of Botryocladia occidentalis (Rhodophyta) contains sulfated galactans (BoSGs) with anti- and procoagulant properties, but their effects on thrombin generation (TG) were fewer explored.
J. A. G. Rodrigues, Jefferson Silva Ferreira Mesquita, Ismael Nilo Lino de Queiroz, J. P. Macedo Feitosa, S. De Aguiar Soares, Ianna Wivianne Fernandes de Araújo, N. M. Barros Benevides   +6 more
semanticscholar   +1 more source

The structure of a galactan sulfate from the red seaweed Bostrychia montagnei

Carbohydrate Research, 2002
The sulfated, methylated galactan isolated from the red seaweed Bostrychia montagnei, showed an unusually narrow structural dispersion. This agaran has the defining linear backbone of alternating 3-linked beta-D-galactopyranosyl units and 4-linked alpha-L-galactopyranosyl and 3,6-anhydrogalactopyranosyl residues.
Maria E R, Duarte, Miguel D, Noseda, Marco A, Cardoso, Siumara, Tulio, Alberto S, Cerezo   +4 more
openaire   +2 more sources

The galactan sulfate from the edible, red alga Porphyra columbina

Carbohydrate Research, 1981
Abstract A galactan sulfate has been isolated from the seaweed Porphyra columbina , and its structure established by a combination of methylation, methanolysis, treatment with alkali followed by methylation, and 13 C-n.m.r. spectroscopy. The polysaccharide belongs to the porphyran class, and consists of 3-linked β- d -galactosyl residues and 4 ...
Donald J. Brasch, Hi Mui Chang, Chaw T. Chuah, Laurence D. Melton   +3 more
openaire   +1 more source

Simple separation of anticoagulant sulfated galactan from marine red algae

Journal of Applied Phycology, 2008
In this study, hot water extracts of 22 red algal species were evaluated for their potential anticoagulant activities. The extracts from eight species (Grateloupia elliptica, Sinkoraena lancifolia, Halymenia dilatata, Grateloupia lanceolata, Lomentaria catenata, Martensia denticulata, Schizymenia dubyi, Chondrus crispus) showed potent activated partial
Seung-Hong Lee, Yasantha Athukorala, Jung-Suck Lee, You-Jin Jeon   +3 more
openaire   +1 more source

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of α-thrombin

Biochimica et Biophysica Acta (BBA) - General Subjects, 2008
Novel compounds presenting anticoagulant activity, such as sulfated polysaccharides, open new perspectives in medicine. Elucidation of the molecular mechanism behind this activity is desirable by itself, as well as because it allows for the design of novel compounds.
Fábio R, Melo, Mariana S, Pereira, Robson Q, Monteiro, Débora, Foguel, Paulo A S, Mourão   +4 more
openaire   +2 more sources

A 2-sulfated, 3-linked α-l-galactan is an anticoagulant polysaccharide

Carbohydrate Research, 2002
Marine alga is an abundant source of sulfated polysaccharides with potent anticoagulant activity. However, several attempts to identify the specific structural features in these compounds, which confer the biological activity, failed due to their complex, heterogeneous structure.
Mariana S, Pereira, Ana-Cristina E S, Vilela-Silva, Ana-Paula, Valente, Paulo A S, Mourão   +3 more
openaire   +2 more sources

Sulfated galactans from the red seaweed Nothogenia fastigiata (Nemaliales, Rhodophyta)

Hydrobiologia, 1990
Fractionation of the cetrimide salts of the sulfated polysaccharides of Nothogenia fastigiata led to the isolation of a complex galactan sulfate. This product showed compositional and molecular weight heterodispersion together with composition-, temperature-, time-, and conformation-dependent molecular associations.
Hernán H. Haines, María C. Matulewicz, Alberto S. Cerezo   +2 more
openaire   +1 more source

Preparation of a sulfated linear (1→4)-β-d-galactan with variable degrees of sulfation

Carbohydrate Polymers, 2000
A linear 1,4-β-d-galactan has been prepared by partial acid hydrolysis of the major lupin seed polysaccharide on a preparative scale. The galactan has been characterized by acetylation and methylation analysis, by GPC, as well as by its 1H- and 13C-NMR-spectra. Sulfation with increasing amounts of SO3-pyridine yielded a series of galactan sulfates with
H Vogl, D.H Paper, G Franz
openaire   +1 more source

Mobility of Sulfate Ester during Structural Determinations of Red Algal Galactans

Botanica Marina, 2002
The polysaccharide from Rhodophyllis membranacea (family Cystocloniaceae) was found to be approximately 80% L-carrageenan together with 20 % of a further precursor-like entity. Alkali treatment of the initial polymer gaveonly ι-carrageenan. A standard methylation of this polysaccharide in NaOH/DMSO gave 95 % of the product as permethylated β ...
I. J. Miller, J. W. Blunt
openaire   +1 more source