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Structure and anti-metapneumovirus activity of sulfated galactans from the red seaweed Cryptonemia seminervis

Carbohydrate Polymers, 2014
The anti-HMPV (human metapneumovirus) activity was determined for sulfated dl-hybrid galactans obtained from the red seaweed Cryptonemia seminervis and their depolymerized products obtained by reductive partial hydrolysis. Structural studies carried out in three homogeneous depolymerized fractions DS-1, DS-2e and DS-3 (Mw of 51.6-63.8 kDa) showed that ...
MIGUEL D Noseda   +2 more
exaly   +3 more sources

Desulfation of sulfated galactans with chlorotrimethylsilane. Characterization of β-carrageenan by 1H NMR spectroscopy

Carbohydrate Research, 2004
A desulfation method using chlorotrimethylsilane for treatment of pyridinium salts of sulfated galactans was developed. It proved to be appropriate for desulfation of polysaccharides of both agar and carrageenan families. In order to evaluate its efficiency in presence of the maximum content of 3,6-anhydrogalactose, it was applied to commercial kappa ...
Adriana Kolender, Maria C Matulewicz
exaly   +3 more sources

Isolation, characterization and bioactive potential of sulfated galactans from Spyridia hypnoides (Bory) Papenfuss

International Journal of Biological Macromolecules, 2018
The sulfated galactans (SG) of mass 16 kDa was purified from S.hypnoides through anion exchange and gel permeation chromatography. The biochemical properties of SG including carbohydrate, 3,6 anhydrogalactose, sulfate, uronic acid, moisture, ash, carbon, hydrogen, nitrogen contents were estimated.
Palaniappan Seedevi   +2 more
exaly   +3 more sources

Immunomodulatory and anti-inflammatory and anticancer activities of porphyran, a sulfated galactan

Carbohydrate Polymers, 2023
Seaweeds are high in bioactive chemicals frequently used to treat human illnesses. Porphyran is a polysaccharide found in the red seaweeds of the genus Porphyra. Porphyran has been discovered to have immunomodulatory, anti-inflammatory activity, and anti-cancer effects via boosting immunity and targeting important apoptotic molecules, making them ...
Biswajita, Pradhan   +2 more
openaire   +2 more sources

Immunostimulating effects of a sulfated galactan from Codium fragile

Carbohydrate Research, 2010
A pyruvylated sulfated galactan from Codium fragile is a highly ramified polysaccharide consisting of 3-linked, 3,6-linked, and non-reducing terminal d-galactose with pyruvate and sulfate groups; the glycan exerts anti-herpes simplex virus type 2 effects in vitro and in vivo.
Jung-Bum, Lee   +3 more
openaire   +2 more sources

Conformation of sulfated galactan and sulfated fucan in aqueous solutions: Implications to their anticoagulant activities

Journal of Molecular Graphics and Modelling, 2007
The discovery of sulfated galactans and sulfated fucans in marine invertebrates with simple and ordered structures opened new perspectives to investigate the biological activity of these molecules and to determine whether different structures confer high affinity for a particular protein. We undertook a conformational analysis of a 2-sulfated, 3-linked
Camila F, Becker   +3 more
openaire   +2 more sources

The structure of a galactan sulfate from the red seaweed Bostrychia montagnei

Carbohydrate Research, 2002
The sulfated, methylated galactan isolated from the red seaweed Bostrychia montagnei, showed an unusually narrow structural dispersion. This agaran has the defining linear backbone of alternating 3-linked beta-D-galactopyranosyl units and 4-linked alpha-L-galactopyranosyl and 3,6-anhydrogalactopyranosyl residues.
Maria E R, Duarte   +4 more
openaire   +2 more sources

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