Results 1 to 10 of about 11,612 (262)
Seaweed-Derived Sulfated Polysaccharides; The New Age Chemopreventives: A Comprehensive Review [PDF]
Prajna Paramita Bhuyan +2 more
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Engineered Sulfated Polysaccharides for Biomedical Applications
AbstractSulfated polysaccharides are ubiquitous in living systems and have central roles in biological functions such as organism development, cell proliferation and differentiation, cellular communication, tissue homeostasis, and host defense. Engineered sulfated polysaccharides (ESPs) are structural derivatives not found in nature but generated ...
Øystein Arlov +4 more
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Photocrosslinkable polysaccharides based on chondroitin sulfate [PDF]
AbstractPhotopolymerizing hydrogels have demonstrated potential for use as a scaffold in numerous tissue‐engineering applications. The majority of photopolymerizing hydrogels are made from purely synthetic polymers. The purpose of this study was to synthesize and characterize photopolymerizing hydrogels derived from the biopolymer chondroitin sulfate ...
Qiang, Li +5 more
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Effects of sulfated polysaccharides on tumour biology
Sulfated polysaccharides can act not only as anticoagulants but also as tumour inhibitors. Recent studies suggest that sulfated polysaccharides could affect tumour cells directly. Sulfated polysaccharides could inhibit the metastasis and proliferation of tumour cells by binding to growth factors and cell adhesion molecules.
X Z, Wu, D, Chen
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[Antiviral action of sulfated polysaccharides].
The literature data on the structure and biological spectrum of sulfated polysaccharides (fucoidans) from the sea brown algae are presented. The review includes the data on the experimental studies and the results of the author's researches on the sulfated polysaccharides inhibitory action on virus adsorption on eukaryotic cells.
I. D. Makarenkova +2 more
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Structure and Bioactivity of Sulfated Polysaccharides
グリコサミノグリカンを含む酸性多糖類は様々な化学的、生物学的な機能を示す。これらの機能の多くは硫酸基の存在に強く依存している。よってこれら多糖類の部分的硫酸化、完全硫酸化あるいは脱硫酸化などの化学的修飾は、硫酸化多糖の示す機能を制御できるものと期待されている。多糖類の化学的修飾に関する論文は数多く、私たちもこれまで多糖類の化学修飾のみならずその生物学的作用に関して検討してきた(構造-活性相関、SAR)。本論文では天然および化学修飾した多糖類の構造活性相関について最近の結果を示す。
Toida, Toshihiko +2 more
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The specificity of interactions between proteins and sulfated polysaccharides [PDF]
Sulfated polysaccharides are capable of binding with proteins at several levels of specificity. As highly acidic macromolecules, they can bind non-specifically to any basic patch on a protein surface at low ionic strength, and such interactions are not likely to be physiologically significant.
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COMPARISON OF THE ANTICOAGULANT ACTION OF SULFATED AND PHOSPHORYLATED POLYSACCHARIDES
Oat spelts xylan (OSX), fucoidan, kappa carrageenan and chondroitin sulfates A and C were sulfated using chlorosulfonic acid-pyridine complex while the first three were phosphorylated using methane sulfonic acid-phosphorous pentoxide mixture. The compounds were isolated as the sodium salts and their in vitro anticoagulant properties were determined by ...
Chemistry Department, Prairie View A&M University, Prairie View, TX 77446, USA ( host institution ) +6 more
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NEUROPROTECTIVE EFFECTS OF SULFATED POLYSACCHARIDES FROM SEAWEED
Currently, neurodegenerative diseases (NDD) occupy a significant place in the structure of disease of the elderly, which dictates the need to find new and effective treatment and prevention of this pathology. At the heart of NDD development is a violation of the metabolism and the conformational change of cellular proteins with subsequent accumulation ...
N N, Besednova +3 more
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The influence of sulfated polysaccharides on the circulating levels of hyaluronan [PDF]
When chondroitin sulfate (CS) or dextran sulfate (DxS) was administered intravenously in rats the levels of circulating hyaluronan (HA) rapidly increased. 70 min after injection the levels were found to be about 10-20 times the initial values. Saline injections were without effect on HA levels.
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