Results 131 to 140 of about 772 (167)
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Characterization and immunomodulatory activity of sulfated galactan from the red seaweed Gracilaria fisheri

International Journal of Biological Macromolecules, 2021
Polysaccharides from the red seaweed Gracilaria fisheri possess many functions, which include antioxidant, antiviral, and antibacterial activities. However, detailed data on their immunomodulatory activities are scarce. Here, we isolated sulfated galactans (SG) from G. fisheri. We found that the predominant SG from G.
Sunisa, Khongthong   +5 more
openaire   +2 more sources

Sulfated galactan is a catalyst of antithrombin-mediated inactivation of α-thrombin

Biochimica et Biophysica Acta (BBA) - General Subjects, 2008
Novel compounds presenting anticoagulant activity, such as sulfated polysaccharides, open new perspectives in medicine. Elucidation of the molecular mechanism behind this activity is desirable by itself, as well as because it allows for the design of novel compounds.
Fábio R, Melo   +4 more
openaire   +2 more sources

A precipitation reaction between certain human G immunoglobulins and sulfated galactans

Immunochemistry, 1971
Abstract During electrophoresis, some pathological sera are seen to precipitate spontaneously in an agar gel and not in an agarose gel. Such sera come from G myelomas or malignant lymphomatosis cases. A similar precipitation is observed when either agaropectin or other sulfated galactans (but not other sulfated polysaccharides) are added to the same ...
P, Burtin, M C, Gendron
openaire   +3 more sources

A new sulfated β-galactan from clams with anti-HIV activity

Carbohydrate Research, 1999
A new polysaccharide composed of galactan sulfate with a beta-(1-->3)-glycosidic linkage has been isolated from the marine clam species Meretrix petechialis. The polysaccharide was homogeneous in its composition containing D-galactose. The glycosidic linkage was examined by 2D DQF-COSY and 2D NOESY spectroscopy. The coupling constant of anomeric proton
C, Amornrut   +7 more
openaire   +2 more sources

Structural and functional insights into sulfated galactans: a systematic review

Glycoconjugate Journal, 2009
Sulfated galactans (SGs) are highly anionic marine galactose-composed homopolysaccharides. Although their structures vary among species, their main features are conserved among phyla. Green algal SGs are quite heterogeneous, although preponderantly composed of 3-beta-D-Galp units.
openaire   +2 more sources

Galactan sulfate of Grateloupia indica: Isolation, structural features and antiviral activity

Phytochemistry, 2007
Natural compounds offer interesting pharmacological perspectives for antiviral drug development with regard to broad-spectrum antiviral properties and novel modes of action. In this study, we have analyzed polysaccharide fractions isolated from Grateloupia indica.
Kausik, Chattopadhyay   +5 more
openaire   +2 more sources

A 2-sulfated, 3-linked α-l-galactan is an anticoagulant polysaccharide

Carbohydrate Research, 2002
Marine alga is an abundant source of sulfated polysaccharides with potent anticoagulant activity. However, several attempts to identify the specific structural features in these compounds, which confer the biological activity, failed due to their complex, heterogeneous structure.
Mariana S, Pereira   +3 more
openaire   +2 more sources

Preparation of a sulfated linear (1→4)-β-d-galactan with variable degrees of sulfation

Carbohydrate Polymers, 2000
A linear 1,4-β-d-galactan has been prepared by partial acid hydrolysis of the major lupin seed polysaccharide on a preparative scale. The galactan has been characterized by acetylation and methylation analysis, by GPC, as well as by its 1H- and 13C-NMR-spectra. Sulfation with increasing amounts of SO3-pyridine yielded a series of galactan sulfates with
H Vogl, D.H Paper, G Franz
openaire   +1 more source

The galactan sulfate from the edible, red alga Porphyra columbina

Carbohydrate Research, 1981
Abstract A galactan sulfate has been isolated from the seaweed Porphyra columbina , and its structure established by a combination of methylation, methanolysis, treatment with alkali followed by methylation, and 13 C-n.m.r. spectroscopy. The polysaccharide belongs to the porphyran class, and consists of 3-linked β- d -galactosyl residues and 4 ...
Donald J. Brasch   +3 more
openaire   +1 more source

The Immunologic Response of Rabbits to Carrageenans, Sulfated Galactans Extracted from Marine Algae

The Journal of Immunology, 1968
Summary Both κ and λ carrageenans, sulfated galactans, elicit formation of precipitating antibodies in rabbits. The carrageenan-anti-carrageenan system follows the kinetics of other well-known antipolysaccharide systems. Both λ and κ carrageenan show a high degree of immunologic specificity; namely, no reaction was observed between ...
K H, Johnston, E L, McCandless
openaire   +2 more sources

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