Results 11 to 20 of about 402,020 (174)

Anti-Thrombin, Anti-Adhesive, Anti-Migratory, and Anti-Proliferative Activities of Sulfated Galactans from the Tropical Green Seaweed, Udotea flabellum. [PDF]

Mar Drugs, 2018
In this study, sulfated polysaccharide-rich extracts were isolated from 22 tropical seaweeds (4 red, 11 brown, and 7 green) found in northeastern Brazil, and evaluated for the role of anticoagulant agents.
Mendes Marques ML, Presa FB, Viana RLS, Costa MSSP, Amorim MOR, Bellan DL, Alves MGCF, Costa LS, Trindade ES, Rocha HAO.   +9 more
europepmc   +2 more sources

Structure, anti-SARS-CoV-2, and anticoagulant effects of two sulfated galactans from the red alga Botryocladia occidentalis. [PDF]

Int J Biol Macromol, 2023
Maurya AK, Sharma P, Samanta P, Shami AA, Misra SK, Zhang F, Thara R, Kumar D, Shi D, Linhardt RJ, Sharp JS, Doerksen RJ, Tandon R, Pomin VH.   +13 more
europepmc   +2 more sources

Occurrence of sulfated galactans in marine angiosperms: evolutionary implications. [PDF]

Glycobiology, 2004
We report for the first time that marine angiosperms (seagrasses) possess sulfated polysaccharides, which are absent in terrestrial and freshwater plants. The structure of the sulfated polysaccharide from the seagrass Ruppia maritima was determined. It is a sulfated D-galactan composed of the following regular tetrasaccharide repeating unit: [3-beta-D ...
R. S. Aquino, A. Landeira-Fernandez, A. Valente, L. Andrade, P. Mourão   +4 more
semanticscholar   +3 more sources

Structure and Anticoagulant Activity of Sulfated Galactans [PDF]

Journal of Biological Chemistry, 2000
We have characterized the structure of a sulfatedd-galactan from the red algae Botryocladia occidentalis. The following repeating structure (-4-α-d-Galp-1→3-β-d-Galp-1→) was found for this polysaccharide, but with a variable sulfation pattern.
W. Farias, A. Valente, M. Pereira, P. Mourão   +3 more
semanticscholar   +2 more sources

Is the antithrombotic effect of sulfated galactans independent of serpin? [PDF]

Journal of Thrombosis and Haemostasis, 2014
Sulfated galactans are polysaccharides with heterogeneous structures that frequently show anticoagulant activity. Their anticoagulant mechanisms are complex and distinct from those observed for heparin. Sulfated galactans act through a combination of effects involving serpin-dependent and serpin-independent mechanisms. Interestingly, these polymers can
A. Quinderé, G. R. Santos, Stephan-Nicollas Oliveira, B. Glauser, B. P. Fontes, I. N. Queiroz, N. Benevides, V. Pomin, P. Mourão   +8 more
semanticscholar   +3 more sources

Sulfated galactans ameliorate the cellular senescence in dermal fibroblast cells

Journal of Agriculture and Food Research
Replicative senescence of dermal fibroblast is the primary mechanism of intrinsic skin aging. Recent research has focused on the different properties of sulfated galactans (SG) derived from the red seaweed Gracilaria fisheri. Therefore, we aimed to investigate the potential impact of SG on anti-aging skin.
Benjamart Pratoomthai, Phennapa Promthale, W. Gangnonngiw, Thirawass Phumyoo, K. Wongprasert   +4 more
semanticscholar   +3 more sources

Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans? [PDF]

Glycobiology, 2002
We attempted to identify the specific structural features in sulfated galactans and sulfated fucans that confer anticoagulant activity. For this study we employed a variety of invertebrate polysaccharides with simple structures composed of well-defined units of oligosaccharides.
M. Pereira, F. Melo, P. Mourão
semanticscholar   +3 more sources

The immunologic response of rabbits to carrageenans, sulfated galactans extracted from marine algae.

The Journal of Immunology, 1968
Both κ and λ carrageenans, sulfated galactans, elicit formation of precipitating antibodies in rabbits. The carrageenan-anti-carrageenan system follows the kinetics of other well-known antipolysaccharide systems.
K. H. Johnston, E. L. Mccandless
semanticscholar   +3 more sources

Antiproliferative activity of glycosaminoglycan-like polysaccharides derived from marine molluscs [PDF]

, 2018
Despite the increasing availability of new classes of cancer treatment, such as immuneand targeted therapies, there remains a need for the development of new antiproliferative/cytotoxic drugs with improved pharmacological profiles that can also ...
Gallagher, Makarenkova, Preobrazhenskaya, Zhang   +3 more
core   +8 more sources

Sulfated Galactans from Gracilaria fisheri with Supplementation of Octanoyl Promote Wound Healing Activity In Vitro and In Vivo.

Macromolecular Bioscience, 2022
Sulfated galactans (SG) isolated from Gracilaria fisheri was partially degraded (DSG), and subsequentially supplemented with octanoyl (DSGO) and sulfate (DSGS) groups.
Tawut Rudtanatip, Somsuda Somintara, Waraporn Sakaew, Jamal El-Abid, M. E. Cano, Kamonwan Jongsomchai, K. Wongprasert, J. Kovensky   +7 more
semanticscholar   +1 more source