The synthesis of cell-wall sulfated galactans proceeds through UDP galactose, a major nucleotide sugar in red seaweed, whilst sulfate is transported through S-transporters into algae.
Diana del Rosario-Santana +2 more
doaj +1 more source
Is there a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans? [PDF]
We attempted to identify the specific structural features in sulfated galactans and sulfated fucans that confer anticoagulant activity. For this study we employed a variety of invertebrate polysaccharides with simple structures composed of well-defined units of oligosaccharides.
Mariana S, Pereira +2 more
openaire +2 more sources
Trehalose as a Possible Precursor of the Sulfated L-Galactan in the Ascidian Tunic [PDF]
Among sulfated polysaccharides, those in the tunic of ascidians are unique: their major constituent sugar is galactose, which occurs exclusively in the L-enantiomeric form. Incorporation of D-[14C]glucose into tunic slices in vitro revealed that the cells epimerize D-glucose into L-galactose during biosynthesis of the sulfated polysaccharides.
P A, Mourão, A M, Assreuy
openaire +2 more sources
Sulfated fucans and a sulfated galactan from sea urchins as potent inhibitors of selectin-dependent hematogenous metastasis [PDF]
Metastasis is responsible for the majority of cancer-associated deaths, though only a very small number of tumor cells are able to efficiently complete all the steps of that process. Tumor cell survival in the bloodstream is one of the limiting aspects of the metastatic cascade.
Felipe C O B Teixeira +5 more
+6 more sources
Structure, biology, evolution, and medical importance of sulfated fucans and galactans [PDF]
Sulfated fucans and galactans are strongly anionic polysaccharides found in marine organisms. Their structures vary among species, but their major features are conserved among phyla. Sulfated fucans are found in marine brown algae and echinoderms, whereas sulfated galactans occur in red and green algae, marine angiosperms, tunicates (ascidians), and ...
Vitor H, Pomin, Paulo A S, Mourão
openaire +2 more sources
A Repeating Sulfated Galactan Motif Resuscitates Dormant Micrococcus luteus Bacteria [PDF]
ABSTRACT Only a small fraction of bacteria can autonomously initiate growth on agar plates. Nongrowing bacteria typically enter a metabolically inactive dormant state and require specific chemical trigger factors or signals to exit this state and to resume growth.
Thomas Böttcher +2 more
openaire +2 more sources
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj +1 more source
Sulfated galactans from red seaweeds and their potential applications [PDF]
Red seaweeds (Rhodophyta) produce a variety of sulfated galactans in their cell wall matrix and intercellular space, contributing up to 50-60 % of their total dry weight.
Lee, Wei Kang +5 more
core +1 more source
Hot water extraction from the red seaweed Asparagopsis taxiformis yielded three extracts which showed sulfated galactans with a D:L-galactose ratio non consistent with carrageenan or agaran backbones.
Ciancia, Marina +9 more
core +1 more source
Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj +1 more source

