Results 31 to 40 of about 772 (167)

The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics

open access: yesMicroorganisms, 2017
Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
doaj   +1 more source

Galactan polysaccharides extraction from invasive algae Asparagopsis armata (Harvey) of the Peniche coast.

open access: yesFrontiers in Marine Science, 2014
Marine macroalgae are important sources of sulfated polysaccharides with different structure according to each species of algae. These compounds from the seaweeds of the division Rhodophyta are mainly galactans consisting entirely of galactose or ...
Marcia Sofia Santos
doaj   +1 more source

Marine medicinal glycomics

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Glycomics is an international initiative aimed to understand the structure and function of the glycans from a given type of cell, tissue, organism, kingdom or even environment, as found under certain conditions.
Vitor Hugo Pomin
doaj   +1 more source

Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges

open access: yesMarine Drugs, 2012
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
doaj   +1 more source

Antioxidant Sulfated Polysaccharide from Edible Red Seaweed Gracilaria birdiae is an Inhibitor of Calcium Oxalate Crystal Formation

open access: yesMolecules, 2020
The genus Gracilaria synthesizes sulfated polysaccharides (SPs). Many of these SPs, including those synthesized by the edible seaweed Gracilaria birdiae, have not yet been adequately investigated for their use as potential pharmaceutical compounds ...
Leticia Castelo Branco Peroba Oliveira   +9 more
doaj   +1 more source

Specific sulfation and glycosylation - a structural combination for the anticoagulation of marine carbohydrates

open access: yesFrontiers in Cellular and Infection Microbiology, 2014
Based on considered achievements of the last 25 years, specific combinations of sulfation patterns and glycosylation types have been proved to be key structural players for the anticoagulant activity of certain marine glycans.
Vitor Hugo Pomin   +1 more
doaj   +1 more source

Anticoagulant properties of a crude sulfated polysaccharide from the red marine alga Halymenia floresia (Clemente) C. Agardh - doi: 10.4025/actascibiolsci.v33i3.6402

open access: yesActa Scientiarum: Biological Sciences, 2011
Alternative sources of anticoagulants have arisen as a result of the increasing demand for safer anticoagulant clinical therapy, and the sulfated polysaccharides of seaweeds have gained attention in biomedicine.
Rodrigo César das Neves Amorim   +4 more
doaj   +1 more source

Sulfated Polysaccharide Extracted from the Green Algae Codium bernabei: Physicochemical Characterization and Antioxidant, Anticoagulant and Antitumor Activity

open access: yesMarine Drugs, 2022
Codium bernabei is a green alga that grows on Chilean coasts. The composition of its structural polysaccharides is still unknown. Hence, the aim of this work is to isolate and characterize the hot water extracted polysaccharide fractions.
Fabian A. Figueroa   +12 more
doaj   +1 more source

Isolation of Sulfated Galactan from Codium fragile and Its Antiviral Effect

open access: yesBiological and Pharmaceutical Bulletin, 2009
A sulfated galactan (FG) was isolated from the green alga, Codium fragile. Chemical analysis revealed that FG mainly consisted of D-galactose with pyruvic acid (12.3%) and sulfate (11.0%). Methylation and NMR analyses showed that FG was composed of -->3)-beta-D-Galp-(1-->, beta-D-Galp-(1--> and -->3,6)-beta-D-Galp-(1--> residue.
Ohta, Yuko   +3 more
openaire   +3 more sources

Sulfated galactans from Gracilaria corticata reprogram metabolism, activate Immunity, promote regeneration, and exhibit anti-melanoma activity

open access: yesiScience
Summary: Sulfated polysaccharides from marine algae hold therapeutic potential, but their mechanisms remain underexplored. This study investigates how distinct sulfated galactans from the red seaweed Gracilaria corticata reprogram cellular metabolism to ...
Amal D. Premarathna   +7 more
doaj   +1 more source

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