Results 31 to 40 of about 772 (167)
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and Mimetics
Glycosaminoglycans (GAGs) are sulfated glycans capable of regulating various biological and medical functions. Heparin, heparan sulfate, chondroitin sulfate, dermatan sulfate, keratan sulfate and hyaluronan are the principal classes of GAGs found in ...
Ariana A. Vasconcelos, Vitor H. Pomin
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Marine macroalgae are important sources of sulfated polysaccharides with different structure according to each species of algae. These compounds from the seaweeds of the division Rhodophyta are mainly galactans consisting entirely of galactose or ...
Marcia Sofia Santos
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Glycomics is an international initiative aimed to understand the structure and function of the glycans from a given type of cell, tissue, organism, kingdom or even environment, as found under certain conditions.
Vitor Hugo Pomin
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Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges
Glycomics turned out to be a very extensive project where its subdivision is consequently emerging. This is seen by the growing number of terminologies used to define subprojects concerning particular classes of bioactive carbohydrates.
Vitor H. Pomin
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The genus Gracilaria synthesizes sulfated polysaccharides (SPs). Many of these SPs, including those synthesized by the edible seaweed Gracilaria birdiae, have not yet been adequately investigated for their use as potential pharmaceutical compounds ...
Leticia Castelo Branco Peroba Oliveira +9 more
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Based on considered achievements of the last 25 years, specific combinations of sulfation patterns and glycosylation types have been proved to be key structural players for the anticoagulant activity of certain marine glycans.
Vitor Hugo Pomin +1 more
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Alternative sources of anticoagulants have arisen as a result of the increasing demand for safer anticoagulant clinical therapy, and the sulfated polysaccharides of seaweeds have gained attention in biomedicine.
Rodrigo César das Neves Amorim +4 more
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Codium bernabei is a green alga that grows on Chilean coasts. The composition of its structural polysaccharides is still unknown. Hence, the aim of this work is to isolate and characterize the hot water extracted polysaccharide fractions.
Fabian A. Figueroa +12 more
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Isolation of Sulfated Galactan from Codium fragile and Its Antiviral Effect
A sulfated galactan (FG) was isolated from the green alga, Codium fragile. Chemical analysis revealed that FG mainly consisted of D-galactose with pyruvic acid (12.3%) and sulfate (11.0%). Methylation and NMR analyses showed that FG was composed of -->3)-beta-D-Galp-(1-->, beta-D-Galp-(1--> and -->3,6)-beta-D-Galp-(1--> residue.
Ohta, Yuko +3 more
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Summary: Sulfated polysaccharides from marine algae hold therapeutic potential, but their mechanisms remain underexplored. This study investigates how distinct sulfated galactans from the red seaweed Gracilaria corticata reprogram cellular metabolism to ...
Amal D. Premarathna +7 more
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