Results 11 to 20 of about 18,229 (68)

Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model [PDF]

Communications Medicine
Background Protein subunit vaccines have a strong track record of efficacy and safety and have been widely applied for prevention of a variety of infectious diseases.
Tyler M. Renner, Matthew Stuible, Martin A. Rossotti, Nazanin Rohani, Yuneivy Cepero-Donates, Janelle Sauvageau, Lise Deschatelets, Renu Dudani, Blair A. Harrison, Jason Baardsnes, Izel Koyuturk, Frank St. Michael, Jennifer J. Hill, Usha D. Hemraz, Anne E. G. Lenferink, Jamshid Tanha, Barbara Fernandes, Antonio Roldao, Michael J. McCluskie, Bassel Akache, Yves Durocher   +20 more
doaj   +3 more sources

Simplified Admix Archaeal Glycolipid Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Enhances Protection from Murine Melanoma. [PDF]

Biomedicines, 2019
Archaeosomes are liposomes composed of natural or synthetic archaeal lipids that when used as adjuvants induce strong long-lasting humoral and cell-mediated immune responses against entrapped antigens.
Stark FC, Agbayani G, Sandhu JK, Akache B, McPherson C, Deschatelets L, Dudani R, Hewitt M, Jia Y, Krishnan L, McCluskie MJ.   +10 more
europepmc   +2 more sources

In Silico Prophage Analysis of Halobacterium salinarum ATCC 33170

Applied Microbiology
The extremophile Halobacterium salinarum is an aerobic archaeon that has adapted to thrive in high-salt environments such as salted fish, hypersaline lakes, and salterns. Halophiles have garnered significant interest due to their unique interactions with
Danielle L. Peters, Bassel Akache, Wangxue Chen, Michael J. McCluskie   +3 more
doaj   +2 more sources

Multivariate method to analyze archaeol in cattle feces [PDF]

, 2023
Producción CientíficaThe analysis of archaeol is necessary in order to obtain greater knowledge about their presence in feces. This study was conducted to explore the capability of using data obtained from two spectroscopic methods, UV-Vis and FTIR, and ...
Pérez González, Clara, Rodríguez Méndez, María Luz, Salvo Comino, Coral, García Cabezón, Ana Cristina   +3 more
core   +2 more sources

Asymmetric synthesis of cyclo-archaeol and beta-glucosyl cyclo-archaeol [PDF]

, 2013
An efficient asymmetric synthesis of cyclo-archaeol and β-glucosyl cyclo-archaeol is presented employing catalytic asymmetric conjugate addition and catalytic epoxide ring opening as the key steps. Their occurrence in deep sea hydrothermal vents has been
Hopmans, E.C., Hopmans, Ellen C., Damsté, J., Ferrer, Catalina, Minnaard, A.J., Fodran, Peter, Minnaard, A., Fodran, P., Ferrer, C., Gibson, R., Minnaard, Adriaan J., Schouten, S., Hopmans, E., Sinninghe Damsté, J.S., Fodran, Peter; id_orcid, Barroso, Santiago, Barroso, S., Schouten, Stefan, Damste, Jaap Sinninghe, Gibson, Robert, Minnaard, Adriaan J.; id_orcid   +20 more
core   +1 more source

Synthesis of Galectin Inhibitors by Regioselective 3′-O-Sulfation of Vanillin Lactosides Obtained under Phase Transfer Catalysis [PDF]

, 2020
Vanillin-based lactoside derivatives were synthetized using phase-transfer catalyzed reactions from per-O-acetylated lactosyl bromide. The aldehyde group of the vanillin moiety was then modified to generate a series of related analogs having variable ...
Roy, René, René Roy, Karima Belkhadem, Yihong Cao, Cao, Yihong, Belkhadem, Karima   +5 more
core   +1 more source

Chemical Synthesis of Glycopeptides containing l‑Arabinosylated Hydroxyproline and Sulfated Tyrosine [PDF]

, 2023
Post-translationally modified peptides are important regulating molecules for living organisms. Here, we report the stereoselective total synthesis of β-1,2-linked l-arabinosylated Fmoc-protected hydroxyproline building blocks and their incorporation ...
Bauke Albada (1781323), Jasper, van de Sande, Jasper W. van de Sande (14790340), Bauke, Albada, Jasper van de Sande, Bauke Albada   +5 more
core   +2 more sources

Hydrothermally Stable, Conformal, Sulfated Zirconia Monolayer Catalysts for Glucose Conversion to 5-HMF [PDF]

, 2015
The grafting and sulfation of zirconia conformal monolayers on SBA-15 to create mesoporous catalysts of tunable solid acid/base character is reported. Conformal zirconia and sulfated zirconia (SZ) materials exhibit both Brönsted and Lewis acidity, with ...
Melero, Juan A., Aston University, D. Robert Brown (1360704), Juan A. Melero (1360701), Marta Granollers (1360692), Gabriel Morales (1360695), University of Huddersfield, Universidad Rey Juan Carlos, Amin Osatiashtiani, Morales, Gabriel, Amin Osatiashtiani (1360689), Karen Wilson, Marta Granollers, Brown, D. Robert, Juan A. Melero, Wilson, Karen, Lee, Adam F., Adam F. Lee, Luca Olivi (1360707), Luca Olivi, Adam F. Lee (1360698), Osastiashtiami, Amin, Olivi, Luca, D. Robert Brown, Sincrotrone Trieste, Brown, D.R., Granollers, Marta, Karen Wilson (459204), Osatiashtiani, Amin, Gabriel Morales   +29 more
core   +1 more source

Archaeol: an indicator of methanogenesis in water-saturated soils [PDF]

, 2012
Oxic soils typically are a sink for methane due to the presence of high-affinity methanotrophic Bacteria capable of oxidising methane. However, soils experiencing water saturation are able to host significant methanogenic archaeal communities ...
Evershed, Richard P, Maxfield, Peter J, Lim, Katie L H, Hornibrook, Edward R C, Pancost, Rich D   +4 more
core   +1 more source

Sulfated Hydrogels in Intervertebral Disc and Cartilage Research [PDF]

, 2021
Hydrogels are commonly used for the 3D culture of musculoskeletal cells. Sulfated hydrogels, which have seen a growing interest over the past years, provide a microenvironment that help maintain the phenotype of chondrocytes and chondrocyte-like cells ...
Paola Bermudez-Lekerika, Gantenbein, Benjamin, Lewis, Christopher L., Wuertz-Kozak, Karin, Bermudez, Paola, Howard, Sloan, Taylor Schofield, Christopher L. Lewis, Daniel Farchione, Lamoca, Mikkael, Iskender Mambetkadyrov, Mambetkadyrov, Iskender, Rivero, Iris V., Benjamin Gantenbein, Karin Wuertz-Kozak, Sloan Howard, Schofield, Taylor, Mikkael Lamoca, Lazarus, Emily, Iris V. Rivero, Farchione, Daniel, Emily Lazarus   +21 more
core   +2 more sources