Results 81 to 90 of about 11,404 (259)

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

Advanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr, Andreas D. Meid, Eric Mühlberg, Manuel Ben Böhmann, Julian Quehenberger, David Wurm, Mikko Gynther, Oliver Spadiut, Gert Fricker, Philipp Uhl   +9 more
wiley   +1 more source

Antiviral Action of Sulfated Polysaccharides

Антибиотики и Химиотерапия, 2020
The literature data on the structure and biological spectrum of sulfated polysaccharides (fucoidans) from the sea brown algae are presented. The review includes the data on the experimental studies and the results of the author's researches on the ...
I. D. Makarenkova, N. N. Besednova, T. S. Zaporozhets   +2 more
doaj  

Antithrombotics from the Sea: Polysaccharides and Beyond

Marine Drugs, 2019
Marine organisms exhibit some advantages as a renewable source of potential drugs, far beyond chemotherapics. Particularly, the number of marine natural products with antithrombotic activity has increased in the last few years, and reports show a wide ...
Francisca Carvalhal, Ricardo R. Cristelo, Diana I. S. P. Resende, Madalena M. M. Pinto, Emília Sousa, Marta Correia-da-Silva   +5 more
doaj   +1 more source

Solomonseal Polysaccharide and Sulfated Codonopsis pilosula Polysaccharide Synergistically Resist Newcastle Disease Virus

PLOS ONE, 2015
Five combinations of three ratios (PS9-sPS1, PS7-sPS3 and PS6-sPS4) were prepared with polysaccharide (PS) and sulfated polysaccharide (sPS). The antiviral activities of these compounds were subsequently compared in vitro using the MTT assay, observation of the virus structure and immunofluorescence.
Cui Liu, Jin Chen, Entao Li, Qiang Fan, Deyun Wang, Cunshuai Zhang, Peng Li, Xiuping Li, Xingying Chen, Shulei Qiu, Zhenzhen Gao, Hongquan Li, Yuanliang Hu   +12 more
openaire   +4 more sources

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

A Metagenome‐Assembled Genome Catalog From the Global Ruminant Microbiomes

Animal Research and One Health, EarlyView.
The Ruminant Gastrointestinal MAG Catalog (RGMC) is a comprehensive global resource offering 40,812 strain‐level genomes across 53 bacterial and 4 archaeal classes. It greatly surpasses prior efforts in scale and diversity, serving as an essential foundation for research in ruminant nutrition, microbial function, and methane mitigation.
Shizhe Zhang, Qiushuang Li, Bingzi Ouyang, Wenxing Wang, Xiang Zhou, Xiumin Zhang, Rong Wang, Zhiliang Tan, Min Wang   +8 more
wiley   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source

Sulfated polysaccharide from Phyllophorella kohkutiensis: Extraction, purification, and bioactivity assessment

Food Chemistry: X
Sulfated polysaccharides from marine sources exhibit diverse biological activities influenced by species and extraction methods. Herein, a sulfated polysaccharide (Pk-P1) was isolated and purified from the edible sea cucumber Phyllophorella kohkutiensis ...
Pornpun Aramsangtienchai, Thanchanok Sirirak, Patchaporn Seesan, Wirunyupha Singrakphon, Jongkonnee Padungkasem, Klaokwan Srisook, Janjarus Watanachote   +6 more
doaj   +1 more source

Design of experiments‐driven optimization of Porphyridium marinum cultivation: impact of operational variables on phycoerythrin and exopolysaccharide production

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Among the Porphyridium genus, Porphyridium marinum exhibits the highest phycoerythrin (PE) content. In this study, the metabolic trade‐off between biomass, PE, and sulfated exopolysaccharide (EPS) production was assessed under varying nitrogen and sulfur availability, light intensity, residence time, and cultivation mode.
Rosaria Tizzani, Agnese Torrisi, Fabrizio Bezzo, Eleonora Sforza   +3 more
wiley   +1 more source

Bioprospecting Ulleungdo‐isolated microalgae for carbon valorization and utilization

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract The growing demand for renewable energy alternatives has intensified global interest in microalgae as versatile bioresources for carbon valorization and bioenergy production. Owing to their rapid growth and biochemical versatility, microalgae provide a sustainable route for converting captured carbon into bioenergy and high‐value products ...
Ha‐Neul Choi, Jeong‐Mi Do, Su‐Bin Park, Myeong‐Jun Gwon, Geum‐Sook Do, Ho‐Sung Yoon   +5 more
wiley   +1 more source