Results 61 to 70 of about 11,665 (263)

Optimization of Sulfation Process of Zizania latifolia Polysaccharide by Response Surface and Its Antioxidant Activity Analysis

Shipin gongye ke-ji
In order to improve the antioxidant activity of Zizania latifolia polysaccharides, sulfate it and explore the optimum modification conditions. Polysaccharides was extracted by water extraction and alcohol precipitation method from Zizania latifolia, then
Xiaoxiao MA, Bing WANG, Huiping LIU, Xin ZHANG, Huihui ZHANG, Can LI, Ying LIU   +6 more
doaj   +1 more source

Pontiella desulfatans gen. nov., sp. nov., and Pontiella sulfatireligans sp. nov., Two Marine Anaerobes of the Pontiellaceae fam. nov. Producing Sulfated Glycosaminoglycan-like Exopolymers

Microorganisms, 2020
Recently, we isolated two marine strains, F1T and F21T, which together with Kiritimatiella glycovorans L21-Fru-ABT are the only pure cultures of the class Kiritimatiellae within the phylum Verrucomicrobiota.
Daan M. van Vliet, Yuemei Lin, Nicole J. Bale, Michel Koenen, Laura Villanueva, Alfons J. M. Stams, Irene Sánchez-Andrea   +6 more
doaj   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

Advanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen, Mingyue Shen, Rui Zhang, Zhibing Huang, Hui Niu, Qiang Yu, Yi Chen, Xiangwen Pan, Liyuan Rong, Huiliang Wen, Jun Yang, Jianhua Xie   +11 more
wiley   +1 more source

Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed. [PDF]

PLoS ONE, 2011
Sulfated polysaccharides from Laminaria saccharina (new name: Saccharina latissima) brown seaweed show promising activity for the treatment of inflammation, thrombosis, and cancer; yet the molecular mechanisms underlying these properties remain poorly ...
Diego O Croci, Albana Cumashi, Natalia A Ushakova, Marina E Preobrazhenskaya, Antonio Piccoli, Licia Totani, Nadezhda E Ustyuzhanina, Maria I Bilan, Anatolii I Usov, Alexey A Grachev, Galina E Morozevich, Albert E Berman, Craig J Sanderson, Maeve Kelly, Patrizia Di Gregorio, Cosmo Rossi, Nicola Tinari, Stefano Iacobelli, Gabriel A Rabinovich, Nikolay E Nifantiev, Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO), Italy   +20 more
doaj   +1 more source

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

The Potential of Sulfated Polysaccharides Isolated from the Brown Seaweed Ecklonia maxima in Cosmetics: Antioxidant, Anti-melanogenesis, and Photoprotective Activities

Antioxidants, 2020
Sulfated polysaccharides prepared from marine algae are potential ingredients in nutraceutical, pharmaceutical, and cosmeceutical industries.
Lei Wang, Thilina U. Jayawardena, Hye-Won Yang, Hyo-Geun Lee, You-Jin Jeon   +4 more
doaj   +1 more source

Structure and Bioactivity of Sulfated Polysaccharides

Trends in Glycoscience and Glycotechnology, 2003
グリコサミノグリカンを含む酸性多糖類は様々な化学的、生物学的な機能を示す。これらの機能の多くは硫酸基の存在に強く依存している。よってこれら多糖類の部分的硫酸化、完全硫酸化あるいは脱硫酸化などの化学的修飾は、硫酸化多糖の示す機能を制御できるものと期待されている。多糖類の化学的修飾に関する論文は数多く、私たちもこれまで多糖類の化学修飾のみならずその生物学的作用に関して検討してきた(構造-活性相関、SAR)。本論文では天然および化学修飾した多糖類の構造活性相関について最近の結果を示す。
Toida, Toshihiko, Chaidedgumjorn, Amornrut, Linhardt, Robert J.   +2 more
openaire   +2 more sources

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source

Hepatoprotective Effects of Extracts and Polysaccharides from Seaweed

Антибиотики и Химиотерапия, 2020
Antioxidants of natural origin are considered as possible agents for prevention and treatment of liver diseases. Marine algae and in particular their extracts and obtained from them sulfated polysaccharides are significant sources of natural antioxidants.
N. N. Besednova, T. S. Zaporozhets, T. A. Kuznetsova, S. P. Kryzhanovskii, N. N. Kovalev, T. N. Zvyagintseva   +5 more
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