OH-Radical Specific Addition to Glutathione S-Atom at the Air–Water Interface: Relevance to the Redox Balance of the Lung Epithelial Lining Fluid [PDF]
, 2015 Antioxidants in epithelial lining fluids (ELF) prevent inhaled air pollutants from reaching lung tissue. This process, however, may upset ELF’s redox balance, which is deemed to be expressed by the ratio of the major antioxidant glutathione (GSH) to its ...
Colussi, Agustín J. +2 more
core +3 more sources
Research advances in the applications of mitochondria‐targeted cyanine dyes in imaging
VIEW, EarlyView.Near‐infrared (NIR) fluorescence imaging, a novel non‐invasive diagnostic tool, plays a crucial role in the imaging and monitoring of solid tumors. At its core are NIR fluorescent dyes, which are widely utilized due to their ability to minimize tissue autofluorescence interference, thereby significantly enhancing the signal‐to‐noise ratio (SNR) and ...
Hongye Liao +8 more
wiley +1 more source
Multiple States of Nitrile Hydratase from Rhodococcus equi TG328-2: Structural and Mechanistic Insights from Electron Paramagnetic Resonance and Density Functional Theory Studies [PDF]
, 2017 Iron-type nitrile hydratases (NHases) contain an Fe(III) ion coordinated in a characteristic “claw setting” by an axial cysteine thiolate, two equatorial peptide nitrogens, the sulfur atoms of equatorial cysteine-sulfenic and cysteine-sulfinic acids, and
Stein, Natalia +9 more
core +1 more source
Linking Superoxide Production and Scavenging in Plant Development
Plant, Cell &Environment, Volume 49, Issue 4, Page 2048-2068, April 2026.ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
wiley +1 more source
The formation of cysteine-tyrosine crosslinks via a sulfenic acid intermediate [abstract] [PDF]
, 2008 only availableCysteine residues in proteins are readily oxidized to sulfenic acids. Sulfenic acids, in turn, can act as potent electrophiles that have been observed to form intrastrand protein crosslinks with neighboring amide or cysteine residues ...
Gates, Kent S. (Kent Stephen), 1962- +2 more
core
Atmospheric chemistry of bioaerosols: heterogeneous and multiphase reactions with atmospheric oxidants and other trace gases. [PDF]
, 2016 Advances in analytical techniques and instrumentation have now established methods for detecting, quantifying, and identifying the chemical and microbial constituents of particulate matter in the atmosphere.
Estillore, Armando D +2 more
core +2 more sources
On‐Demand Chemically Degradable Hydrogels for Biological Applications
ChemBioChem, Volume 27, Issue 6, 27 March 2026.This review explores the mechanisms and kinetics of chemically induced on‐demand degradation in hydrogels designed for painless dressing removal and traceless dissolution across various biological applications. Covalent bond cleavage and noncovalent disruption triggers are compared, highlighting opportunities for load‐bearing scaffolds with faster ...
Xinyi Sheng, Justin Kim
wiley +1 more source
Ozone Oxidizes Glutathione to a Sulfonic Acid [PDF]
, 2009 Biosurfaces are universally covered with fluid microfilms containing reduced glutathione (GSH) and other antioxidants whose putative roles include the detoxification of ambient ozone (O_3).
Colussi, A. J. +2 more
core +1 more source
The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases [PDF]
, 2015 Hydrogen peroxide is an important regulator of protein tyrosine phosphatase activity via reversible oxidation. However, the role of iron in this reaction has not been yet elucidated. Here we compare the influence of hydrogen peroxide and the ferrous iron
Alicja Kuban-Jankowska +5 more
core +1 more source
Medical Gas Plasma Inactivates Adenoviruses via Capsid Oxidation
Small, Volume 22, Issue 15, 12 March 2026.Oxidative modification of three adenoviral capsid proteins after gas plasma treatment. Schematic representation of the viral infection process, starting with the initial attachment of the virus via its fiber protein binding to the cellular receptors (CAR and/or CD46). In the secondary attachment step, the penton base binds to integrin structures on the
Anke Schmidt +7 more
wiley +1 more source