Results 71 to 80 of about 155,517 (152)
Neonatal molybdenum cofactor deficiency and ectopia lentis in a Saudi Arabian patient
International Journal of Pediatrics & Adolescent Medicine, 2014 Molybdenum cofactor deficiency (MCD) is a rare and ultimately fatal metabolic dis-ease that results in extensive neurodegeneration in early infancy. The causal association of MCD with sulfite oxidase deficiency, a known cause of subluxed lenses (ectopia ...
Meshaal A. Al-Obaidalla +3 more
doaj +1 more source
A Computational Investigation Into The Catalytic Activity Of A Diselenolene Sulfite Oxidase Biomimetic Complex [PDF]
, 2016 Molybdenum is the only 4d-metal found in almost all life. One such molybdenum-containing enzyme is sulfite oxidase which also contains the dithiolene-molybdopterin ligand.
Bushnell, Eric A.C.
core +1 more source
On the Difference Between Additive and Subtractive QM/MM Calculations
Frontiers in Chemistry, 2018 The combined quantum mechanical (QM) and molecular mechanical (MM) approach (QM/MM) is a popular method to study reactions in biochemical macromolecules. Even if the general procedure of using QM for a small, but interesting part of the system and MM for
Lili Cao, Ulf Ryde
doaj +1 more source
Isolated sulfite oxidase deficiency in the newborn: Lactic acidaemia and leukoencephalopathy
, 2007 We report a newborn with progressive leukoencephalopathy and lactic acidaemia, diagnosed with isolated sulfite oxidase deficiency. We show that low plasma total homocysteine (PTHcy) is a valuable early indicator of sulfite oxidase dysfunction, providing ...
Hendson, G +6 more
core +1 more source
Loss of sulfite oxidase activity and outer membrane damage in rat hepatic mitochondria during CCl4 poisoning [PDF]
, 1977 The activity of sulfite oxidase increased in intact rat hepatic mitochondria and decreased in solubilized mitochondria during poisoning by CCl4. During acute damage the sulfite oxidase activity of the post-mitochondrial supernate increased, while the ...
Timothy Pastoor +9 more
core +1 more source
FEBS Open Bio, Volume 16, Issue 7, Page 1314-1327, July 2026.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Crop JournalThe objective of this study was to determine how the rice receptor-like cytoplasmic kinase OsBSR1 positively regulates broad-spectrum disease resistance.
Mengtian Pei +6 more
doaj +1 more source
[Mo(TmMe)(O)2Cl]: An Alternative Functional Model of Sulfite Oxidase†
, 2016 The hydrotris(methimazolyl)borate anion (TmMe) has been used to synthesize an alternative functional model ([Mo(TmMe)(O)2Cl]) of the metalloenzyme sulfite oxidase.
Lorraine T. Gibson (2492623) +3 more
core +1 more source
Structure-Function Studies in Sulfite Oxidase with Altered Active Sites
, 2010 Sulfite oxidase, a metabolically important enzyme, catalyzes the physiologically critical conversion of sulfite to sulfate in the terminal step of the degradation of sulfur containing compounds.
Qiu, James
core
, 2007 Animal tissues are exposed to sulfite used as a preservative in food and drugs, and generated from the catabolism of sulfur-containing amino acids. Sulfite, which is a very reactive and potentially toxic molecule, is detoxified by the enzyme sulfite ...
Atsak, Piray. +3 more
core +1 more source