Identification of dfrA14 in two distinct plasmids conferring trimethoprim resistance in Actinobacillus pleuropneumoniae [PDF]
, 2015 OBJECTIVES: The objective of this study was to determine the distribution and genetic basis of trimethoprim resistance in Actinobacillus pleuropneumoniae isolates from pigs in England.
Alexander W. Tucker +17 more
core +3 more sources
N-(2-Phenoxy-4-(3-phenoxyprop-1-ynyl)phenyl)methane Sulfonamide
Molbank, 2012 The title compound, N-(2-phenoxy-4-(3-phenoxyprop-1-ynyl)phenyl) methanesulfonamide was synthesized in high yield by Sonogashira cross coupling of N-(4-iodo-2-phenoxyphenyl)methanesulfonamide with 3-phenoxyprop-1-yne.
Shylaprasad Durgadas +2 more
doaj +1 more source
Interfacial Photoelectrochemistry in Organic Synthesis
Angewandte Chemie International Edition, Accepted Article.Photoelectrodes have traditionally enjoyed widespread attention as heterogeneous catalysts for the activation of water and CO2 in energy research, while photoelectrochemistry with homogeneous molecular catalysts dominates the activations of more complex molecules in organic synthesis.
Gabriel Chan +4 more
wiley +1 more source
Identification of Small-Molecule Inhibitors against Meso-2, 6-Diaminopimelate Dehydrogenase from Porphyromonas gingivalis [PDF]
, 2015 Species-specific antimicrobial therapy has the potential to combat the increasing threat of antibiotic resistance and alteration of the human microbiome.
Chen, Weihau +7 more
core +5 more sources
Angewandte Chemie International Edition, Accepted Article.This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Identification and synthesis of metabolites of the new antiglaucoma drug
Research Results in PharmacologyIntroduction: The determination of biotransformation products is an essential part of the preclinical trial of original medicines. These studies have not been conducted before for the new drug 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide.
Alexander L. Khokhlov +8 more
doaj +1 more source
Sulfonamide drugs: structure, antibacterial property, toxicity, and biophysical interactions
Biophysical Reviews, 2021 Aben Ovung, Jhimli Bhattacharyya
semanticscholar +1 more source
Effect of Pyrolysis on the Removal of Antibiotic Resistance Genes and Class I Integrons from Municipal Wastewater Biosolids [PDF]
, 2018 Wastewater biosolids represent a significant reservoir of antibiotic resistance genes (ARGs). While current biosolids treatment technologies can reduce ARG levels in residual wastewater biosolids, observed removal rates vary substantially.
Kappell, Anthony D. +2 more
core +1 more source