Results 71 to 80 of about 46,253 (290)
Identification of biological sulfonamide degradation
, 2018 Sulfonamides are among the most administered antibiotics, leading to a release of more than 20’000 tons per year into the biosphere. Due to their physicochemical properties, they are classified as photolytically- and thermally stable. As they do not tend
Ricken, Benjamin
core +1 more source
, 2023 Bruton\u27s tyrosine kinase (BTK) is a promising molecular target for several human B-cell-related autoimmune disorders, inflammation, and haematological malignancies.
Marián , Hajdúch +7 more
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American Journal of Industrial Medicine, EarlyView.ABSTRACT Introduction Firefighters may experience occupational exposure to per‐ and polyfluoroalkyl substances (PFAS). Volunteer firefighters make up 65% of the US fire service, but their serum PFAS profiles have not been well characterized. This study aims to (1) describe PFAS serum profiles among US volunteer firefighters from 9 states enrolled in ...
Katherine A. Lubina +16 more
wiley +1 more source
Angewandte Chemie, EarlyView.Enantioselective aminoarylation of ortho‐allyl anilines is achieved under mild conditions. Key to success is the electrostatically‐directed nature of the key aminopalladation step, achieved by using the sulfonated chiral ligand sSPhos on palladium. A detailed study of electronic trends allows tuning of the sulfonamide protecting group to enable good ...
Max Kadarauch +4 more
wiley +2 more sources
Identification and synthesis of metabolites of the new antiglaucoma drug
Research Results in PharmacologyIntroduction: The determination of biotransformation products is an essential part of the preclinical trial of original medicines. These studies have not been conducted before for the new drug 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide.
Alexander L. Khokhlov +8 more
doaj +1 more source
Synthesis of Sulfonamide-Bridged Glycomimetics
, 2016 A flexible and short synthesis of sulfonamide-bridged di-, tri-, tetra-, and octasaccharide glycomimetics was accomplished by reaction of glycosyl thioacetates with amino sugar substrates. The chemistry to incorporate the sulfonamide linker in place of a
Hugues Driguez (678527) +3 more
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Angewandte Chemie, EarlyView.Photochemically generated phosphoryl radicals from iminyl phosphines enable strain‐release addition to azabicyclobutanes, providing access to elusive N‐phosphoryl azetidines. Combined experimental, computational, and EPR studies reveal an unconventional water‐assisted photoredox pathway.
Chandu G. Krishnan +4 more
wiley +2 more sources
Natural Bond orbital Acetamide and Sulfonamide
, 2020 In this theoretical study we used density functional theory to calculate the molecular structures of Sulfonamide and Acetamide Compounds C12H11NSO and C8H9NO.
Ali Rahmani +10 more
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1,2,3,4-Tetrahydroisoquinoline-2-sulfonamide
, 2008 The title compound, C9H12N2O2S, is a useful precursor of a variety of modified sulfonamide molecules. Due to the importance of these molecules in biological systems (antibacterials, antidepressants and many other applications), there is a growing ...
Berredjem, M. +7 more
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Angewandte Chemie, EarlyView.Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source