Results 61 to 70 of about 90,509 (255)

Identification and synthesis of metabolites of the new antiglaucoma drug

Research Results in Pharmacology
Introduction: The determination of biotransformation products is an essential part of the preclinical trial of original medicines. These studies have not been conducted before for the new drug 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide.
Alexander L. Khokhlov, Ilya I. Yaichkov, Anton А. Shetnev, Sergey A. Ivanovsky, Mikhail K. Korsakov, Mikhail A. Alexeev, Olga A. Gasilina, Nikita N. Volkhin, Sergey S. Petukhov   +8 more
doaj   +1 more source

Synthesis of 1 alpha,25-Dihydroxyvitamin D Analogues Featuring a S-2-symmetric CD-ring Core [PDF]

, 2009
Three analogues of 1 alpha,25-dihydroxyvitamin D-3 (calcitriol), featuring a transfused decalin C, D-core with local S-2-symmetry, and possessing identical side-chain and seco-B,A-ring structures, have been synthesized starting from readily available ...
De Clercq, Pierre, Minne, Garrett
core   +2 more sources

Modeling the hydrolysis of perfluorinated compounds containing carboxylic and phosphoric acid ester functions, alkyl iodides, and sulfonamide groups [PDF]

, 2009
Temperature dependent rate constants were estimated for the acid- and base-catalyzed and neutral hydrolysis reactions of perfluorinated telomer acrylates (FTAcrs) and phosphate esters (FTPEs), and the SN1 and SN2 hydrolysis reactions of fluorotelomer ...
Kaya Forest, Sierra Rayne
core   +1 more source

Residues of Tetracycline, Erythromycin, and Sulfonamides in Beef, Eggs, and Honey from Grocery Stores in Knoxville, Tennessee, USA: Failure of Cooking to Decrease Drug Concentrations

Veterinary Sciences
This study evaluated the concentrations of tetracycline, erythromycin, and sulfonamide in beef, eggs, and honey products sold at grocery stores and whether standard cooking to 160 °F (71 °C) reduced the concentrations of antimicrobials spiked into the ...
Shamim Sarkar, Stephen A. Kania, Mohamed A. Abouelkhair, Brian Whitlock, Chika C. Okafor   +4 more
doaj   +1 more source

Effect of sulfonamide pollution on the growth of manure management candidate Hermetia illucens.

PLoS ONE, 2019
Antibiotics are commonly used in livestock and poultry farming. Residual antibiotics in manure may lead to antibiotic pollution of soil, surface water, and groundwater through land application and run-off rainfall.
Qiao Gao, Wenhui Deng, Zhenghui Gao, Mengya Li, Wen Liu, Xiaoping Wang, Fen Zhu   +6 more
doaj   +1 more source

(E)-4-Amino-N-(1,2-dihydropyridin-2-ylidene)benzenesulfonamide nitromethane monosolvate

Acta Crystallographica Section E, 2012
In the title solvate, C11H11N3O2S·CH3NO2, the dihedral angle between the benzene ring and the N-containing ring is 85.94 (11)°, and an approximate V shape arises for the sulfonamide molecule.
Mostafa M. Ghorab, Mansour S. Al-Said, Hazem A. Ghabbour, Suchada Chantrapromma, Hoong-Kun Fun   +4 more
doaj   +1 more source

Spontaneous formation of optically induced surface relief gratings [PDF]

, 2009
A model based on Fick's law of diffusion as a phenomenological description of the molecular motion, and on the coupled mode theory, is developped to describe single-beam surface relief grating formation in azopolymers thin films. It allows to explain the
Bellini B, E Ortyl, H Leblond, J-M Nunzi, Lefin P, R Barille, S Ahmadi-Kandjani, S Kucharski, Sanchez F   +8 more
core   +4 more sources

Neuropharmacological Assessment of Sulfonamide Derivatives of Para-Aminobenzoic Acid through In Vivo and In Silico Approaches

Drugs and Drug Candidates
Background/Objectives: Alzheimer’s disease (AD), a complex neurogenerative disorder, manifests as dementia and concomitant neuropsychiatric symptoms, including apathy, depression, and circadian disruption.
Ankit Ganeshpurkar, Ravi Singh, Pratigya Tripathi, Qadir Alam, Sairam Krishnamurthy, Ashok Kumar, Sushil Kumar Singh   +6 more
doaj   +1 more source

N-(1-Allyl-1H-indazol-5-yl)-4-methoxybenzenesulfonamide hemihydrate

Acta Crystallographica Section E, 2013
In the title compound, C17H17N3O3.0.5H2O, the indazole system makes a dihedral angle of 46.19 (8)° with the plane through the benzene ring and is nearly perpendicular to the allyl group, as indicated by the dihedral angle of 81.2 (3 ...
Hakima Chicha, El Mostapha Rakib, Detlef Geffken, Mohamed Saadi, Lahcen El Ammari   +4 more
doaj   +1 more source

Improved catalytic activity of ruthenium–arene complexes in the reduction of NAD+ [PDF]

, 2012
A series of neutral Ru-II half-sandwich complexes of the type [(eta(6)-arene)Ru(N,N')Cl] where the arene is para-cymene (p-cym), hexamethylbenzene (hmb), biphenyl (bip), or benzene (bn) and N,N' is N-(2-aminoethyl) -4-(trifluoromethyl)benzenesulfonamide (
Abraha Habtemariam, Canivet J., Carrión M. C., Chen Q., Clayden J., Creutz C., Dibenedetto A., Fish R. H., Grau M. M., Grimme S., Guy J. Clarkson, Habtemariam A., Haquette P., Held M., Hileman E. O., Joan J. Soldevila-Barreda, Khan J. A., Kim Y. H., Leiva C., Li X., Lo H. C., Maenaka Y., Martins J. E. D., Matharu D. S., Matthew C. K., Morris R. E., Neese F., Noyori R., Peacock A. F. A., Peter J. Sadler, Pieter C. A. Bruijnincx, Robert J. Deeth, Robertson A., Romain C., Ruppert R., Sandoval C. A., Schäfer A., Sheldrick G. M., Sinnecker S., Tan J., Thai T., Wang C., Wang F., Watanabe M., Weckbecker A., Weigend F., Wolfson A., Wu J., Wu X., Yan Y. K., Ying W., Zhou Z., Zhou Z.   +52 more
core   +2 more sources