Results 151 to 160 of about 71,069 (237)

A novel sulfonamide derivative suppresses gastrointestinal cancer progression by targeting Axin2 and β-catenin. [PDF]

Sci Rep
Li X, Wen H, Chang L, Xue X, Xi H, Hu R, Rong M, Zheng P, Liu S.   +8 more
europepmc   +1 more source

First-in-Class Dual PDGFR/Carbonic Anhydrase IX/XII Inhibitors: 6,7-Dimethoxyquinoline-Sulfonamides as Promising Antileukemic Agents. [PDF]

J Med Chem
Roshdy E, Řezníčková E, Elbadawi MM, Celik I, Giovannuzzi S, Veselá D, Vojáčková V, Krňávková P, Nocentini A, Supuran CT, Kryštof V, Eldehna WM, Abe M.   +12 more
europepmc   +1 more source

Computational insights into novel inhibitors: virtual screening of small molecules against human carbonic anhydrase II. [PDF]

Front Chem
Arunachalam S, M M B, Gnanasekaran R.
europepmc   +1 more source

Machine Learning Prediction of Laccase‐Catalyzed Oxidation of Aromatic Compounds Using Curated Enzyme‐Specific Datasets

Journal of Computational Chemistry, Volume 47, Issue 7, March 15, 2026.
We curate laccase‐substrate datasets and train five classifiers, from regularized logistic regression to tree‐based models and ChemBERTa, to predict whether a substrate will be oxidized. Feature importance and attention maps projected onto molecular substructures make the predictions interpretable and useful for pre‐screening before the bench ...
Yulia Kulagina, Christian Goldhahn, Ramon Weishaupt, Mark Schubert   +3 more
wiley   +1 more source

Identification of Sulfonamide-Vinyl Sulfone/Chalcone and Berberine-Cinnamic Acid Hybrids as Potent DENV and ZIKV NS2B/NS3 Allosteric Inhibitors. [PDF]

Int J Mol Sci
Mahalapbutr P, Hengphasatporn K, Manimont W, Vajarintarangoon L, Shigeta Y, Bhat N, Aiebchun T, Nutho B, Hannongbua S, Rungrotmongkol T.   +9 more
europepmc   +1 more source

Hydroxylamine-O-sulfonic acid - a versatile synthetic reagent [PDF]

, 1980
Wallace, RG
core  

Self‐Immolative Systems in Diagnostic and Therapeutic Applications

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Self‐Immolative Systems enable the precise, residue‐free release of active molecules, drugs, probes, or sensors, via cyclization or elimination, triggered by specific stimuli. Their versatility drives advances in drug delivery, diagnostics, nanotechnology, materials chemistry, and biosensing, offering chemists control over molecular activation and ...
Windbedema Prisca Ouédraogo, Thomas Cailly, Valérie Collot   +2 more
wiley   +1 more source

Scaffold-Based Libraries Versus Make-on-Demand Space: A Comparative Assessment of Chemical Content. [PDF]

ChemMedChem
Bui L, Djikic-Stojsic T, Bret G, Bihel F, Kellenberger E.   +4 more
europepmc   +1 more source

Electrochemical Dehydration of Carboxamides to Their Nitriles

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
Electrochemical dehydration of carboxamides to nitriles is achieved using thiocyanate‐mediated activation, avoiding stoichiometric reagents. In an undivided cell at ambient conditions, 18 aromatic and aliphatic substrates give good‐to‐excellent yields (up to 84%) with functional‐group tolerance. Cyclic voltammetry supports an EC‐type‐mediated oxidation.
Enrico Lunghi, Annemijn M. van Koten, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

Retrospective cohort study on the development of keratoconjunctivitis sicca in dogs treated with trimethoprim sulfonamide: a VetCompass Australia study. [PDF]

J Vet Intern Med
Hardefeldt LY, Scarborough R, Hur B.
europepmc   +1 more source