Results 151 to 160 of about 77,925 (335)

Determining the prevalence and genetic diversity of plasmid-mediated sulfonamide resistance in Escherichia coli from commercial broiler samples

open access: yesPoultry Science
: Sulfonamides are commonly used antibacterials in commercial poultry, contributing toward the development of multidrug-resistant (MDR) phenotypes among Escherichia coli and that has emerged as global concern.
Muhammad Asif Zahoor   +7 more
doaj  

Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors [PDF]

open access: yes, 2012
Alan H. Fairlamb   +53 more
core   +3 more sources

Advances in Mechanochemical Methods for One‐Pot Multistep Organic Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Mechanochemical synthesis has emerged as a powerful and more sustainable alternative to conventional solution‐based methods, offering advantages such as no or only minimal solvent use, reduced reaction times, and simplified operational conditions.
Michael Schnürch, Nina Biedermann
wiley   +1 more source

Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate, and Imidazole Functional Groups in the Major Groove

open access: yesChemistry – A European Journal, EarlyView.
A series of 2’‐deoxyribonucleoside 5’‐O‐triphosphates bearing functional groups of amino acid side chains in enzyme active sites (OH, SH, COOH, and imidazole) were synthesized and used for enzymatic synthesis of hypermodified DNA displaying these substituents in the major groove mimicking peptides or proteins. Abstract We designed and synthesized a set
Lukáš Kaiser   +4 more
wiley   +1 more source

Strategy‐Level Prodrug Synthesis

open access: yesChemistry – A European Journal, Accepted Article.
Organic synthesis uniquely provides opportunities to access molecules that serve defined purposes. Medicinal chemistry illustrates this attribute well with prodrug design, whereby a drug undergoes a late‐stage conversion to a conditionally responsive active medicinal agent (AMA), being a notable example.
Paul Geaneotes, Paul Floreancig
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

In Vitro Action of Sulfonamides on Clostridia [PDF]

open access: bronze, 1944
G. B. Reed, J. H. Orr, Robert W. Reed
openalex   +1 more source

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