Results 251 to 260 of about 77,925 (335)

Exploring aliphatic sulfonamides as multiclass inhibitors of the carbonic anhydrases from the pathogen bacterium Vibrio cholerae. [PDF]

open access: yesArch Pharm (Weinheim)
Paoletti N   +7 more
europepmc   +1 more source

Ring‐Opening Metathesis Polymerization of Levoglucosenone‐Derived Enyne Monomers

open access: yesJournal of Polymer Science, EarlyView.
ABSTRACT Levoglucosenone (LGO) has emerged as a versatile synthon in target‐oriented synthesis due to its availability from cellulose. While its functionality and chirality have found direct use as a small molecule building block, translation to polymerization has been more challenging.
Alec B. Pabarue   +4 more
wiley   +1 more source

Neuroprotective thiazole sulfonamides against 6-OHDA-induced Parkinsonian model: in vitro biological and in silico pharmacokinetic assessments. [PDF]

open access: yesRSC Adv
Ruankham W   +9 more
europepmc   +1 more source

Non‐Thermal Plasma Oxidation Processes for the Removal of Pharmaceuticals in Water: Diclofenac and Diclofenac/Carbamazepine Mixture

open access: yesPlasma Processes and Polymers, EarlyView.
The results of the biological tests of the treated solutions by NTP were systematically compared to the initial solutions without plasma treatment (w/o plasma) ones. The variations of viability of the cells for DCF + CBZ mix could be explained by the concentrations of the produced species during the plasma treatment.
Manoj P. Rayaroth   +7 more
wiley   +1 more source

Discovery of Novel Nav1.7-Selective Inhibitors with the 1H-Indole-3-Propionamide Scaffold for Effective Pain Relief. [PDF]

open access: yesResearch (Wash D C)
Wang G   +15 more
europepmc   +1 more source

Comprehensive Parent‐Metabolite PBPK/PD Modeling Insights Into Methotrexate Personalized Dosing Strategies in Patients With Rheumatoid Arthritis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 4, Page 695-705, April 2025.
ABSTRACT Rheumatoid arthritis (RA) is a major public health concern, which can cause serious outcomes. Low‐dose methotrexate (MTX) is a cornerstone in RA treatment, but there is significant heterogeneity in clinical response. To evaluate underlying sources of pharmacokinetic variability and clinical response of MTX, a physiologically based ...
Xin Wang   +4 more
wiley   +1 more source

Efflux-Enhanced Imidazoquinolines To Exploit Chemoresistance. [PDF]

open access: yesACS Omega
Haroon M   +7 more
europepmc   +1 more source

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