Results 271 to 280 of about 77,925 (335)

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, EarlyView.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

Iatrogenic Primary Hypothyroidism Associated With Sulfamethoxazole-Trimethoprim Treatment of Nocardiosis in a Cat. [PDF]

open access: yesJ Vet Intern Med
Alexander D   +7 more
europepmc   +1 more source

In Vitro CO-Releasing and Antioxidant Properties of Sulfonamide-Based CAI-CORMs in a H<sub>2</sub>O<sub>2</sub>-Stimulated Human Achilles Tendon-Derived Cell Model. [PDF]

open access: yesMolecules
Berrino E   +11 more
europepmc   +1 more source

Evaluating the impact of general practice pharmacist‐led person‐centred medicines reviews on medicines appropriateness and patient‐reported outcome measures

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs).
Clare Kinahan   +9 more
wiley   +1 more source

Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX. [PDF]

open access: yesElife
Vaškevičius A   +21 more
europepmc   +1 more source

RBM39 Promotes Base Excision Repair to Facilitate the Progression of HCC by Stabilising OGG1 mRNA

open access: yesCell Proliferation, EarlyView.
Targeting RBM39 attenuates BER via destabilising OGG1 mRNA and potentiates KBrO3‐induced oxidative stress in HCC. Our study represents a valuable treatment strategy combining indisulam and an oxidative stress inducer in HCC. ABSTRACT Targeting base excision repair (BER) has been an attractive strategy in cancer therapeutics.
Hongda An   +7 more
wiley   +1 more source

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