Results 321 to 330 of about 115,474 (373)
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Sulfonamide synthesis under green conditions
, 2021Sulfonamide moiety is the backbone of various antimicrobial, anticancer, antiglaucoma, anticonvulsant, uricosuric agents, and numerous other drugs. The age-old demand of sulfonamides as powerful antimicrobial agents is still in vogue and will never lose ...
Shovan Mondal
semanticscholar +1 more source
Clinical Reviews in Allergy & Immunology, 2021
Sulfonamides, particularly antimicrobial sulfonamides, have been implicated as a common cause of a spectrum of hypersensitivity reactions. Immediate IgE-mediated reactions have been reported but are much less common than delayed cutaneous reactions. Delayed cutaneous reactions range from benign exanthems to severe cutaneous reactions such as Stevens ...
Timothy G Chow, David A Khan
openaire +2 more sources
Sulfonamides, particularly antimicrobial sulfonamides, have been implicated as a common cause of a spectrum of hypersensitivity reactions. Immediate IgE-mediated reactions have been reported but are much less common than delayed cutaneous reactions. Delayed cutaneous reactions range from benign exanthems to severe cutaneous reactions such as Stevens ...
Timothy G Chow, David A Khan
openaire +2 more sources
Sulfonamide inhibitors: a patent review 2013-present
Expert Opinion on Therapeutic Patents, 2018Introduction: Sulfonamide compounds are significant class of synthetic bacteriostatic antibiotics still which used today for the therapy of bacterial infections and those caused by other microorganisms.
I. Gulcin, Parham Taslimi
semanticscholar +1 more source
Recent Development of Sulfonyl or Sulfonamide Hybrids as Potential Anticancer Agents: A Key Review.
Anti-Cancer Agents in Medicinal Chemistry, 2018Cancer is the second leading cause of death worldwide. There is always a huge demand for novel anticancer drugs and diverse new natural or synthetic compounds are developed continuously by scientists.
K. P. Rakesh +6 more
semanticscholar +1 more source
Chemistry, 2018
The first zinc-binding group (ZBG) to have been identified as inhibitor of the metallo-enzymes carbonic anhydrases (CA, EC 4.2.1.1) was the sulfonamide. From then on several classes of zinc-binders have been described.
A. Nocentini, P. Gratteri, C. Supuran
semanticscholar +1 more source
The first zinc-binding group (ZBG) to have been identified as inhibitor of the metallo-enzymes carbonic anhydrases (CA, EC 4.2.1.1) was the sulfonamide. From then on several classes of zinc-binders have been described.
A. Nocentini, P. Gratteri, C. Supuran
semanticscholar +1 more source
Angewandte Chemie, 2018
A copper-catalyzed asymmetric radical oxytrifluoromethylation of alkenyl oxime and Togni's reagent has been successfully developed, thereby providing straightforward access to CF3 -containing isoxazolines bearing α-tertiary stereocenters with excellent ...
Xi-Tao Li +4 more
semanticscholar +1 more source
A copper-catalyzed asymmetric radical oxytrifluoromethylation of alkenyl oxime and Togni's reagent has been successfully developed, thereby providing straightforward access to CF3 -containing isoxazolines bearing α-tertiary stereocenters with excellent ...
Xi-Tao Li +4 more
semanticscholar +1 more source
Chloride-Mediated Apoptosis-Inducing Activity of Bis(sulfonamide) Anionophores.
Journal of the American Chemical Society, 2016Transmembrane anion transport modality is enjoying a renewed interest because of recent advances toward anticancer therapy. Here we show bis(sulfonamides) as efficient receptors for selective Cl(-) ion binding and transport across lipid bilayer membranes.
T. Saha +4 more
semanticscholar +1 more source
, 2016
Pertussis is a respiratory transmitted disease affecting approximately 23% of the worlds’ population. It is causes by Bordetella Pertussis [1-23]. The emergence of Multiple-Drug-Resistant (MDR) Pertussis has focused the attention of the scientific ...
A. Heidari
semanticscholar +1 more source
Pertussis is a respiratory transmitted disease affecting approximately 23% of the worlds’ population. It is causes by Bordetella Pertussis [1-23]. The emergence of Multiple-Drug-Resistant (MDR) Pertussis has focused the attention of the scientific ...
A. Heidari
semanticscholar +1 more source
Journal of Medicinal Chemistry, 2016
α-Carbonic anhydrase of Helicobacter pylori (HpαCA) plays an important role in the acclimation of this oncobacterium to the acidic pH of the stomach. Sulfonamide inhibitors of HpαCA possess anti-H. pylori activity.
J. Modak +3 more
semanticscholar +1 more source
α-Carbonic anhydrase of Helicobacter pylori (HpαCA) plays an important role in the acclimation of this oncobacterium to the acidic pH of the stomach. Sulfonamide inhibitors of HpαCA possess anti-H. pylori activity.
J. Modak +3 more
semanticscholar +1 more source