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Antiviral Sulfonamide Derivatives
Mini-Reviews in Medicinal Chemistry, 2004The sulfonamides constitute an important class of drugs, with several types of pharmacological agents possessing antibacterial, anti-carbonic anhydrase, diuretic, hypoglycemic, antithyroid and anticancer activity among others. A large number of structurally novel sulfonamide derivatives have ultimately been reported to show substantial antiviral ...
SUPURAN, CLAUDIU TRANDAFIR+3 more
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Acta Crystallographica Section C Crystal Structure Communications, 2000
In the title molecule, C15H11NO4S, the phenyl and benzene rings are quite planar, with maximum deviations from planarity of 0.009 (2) and 0.004 (1) A, respectively. The γ-pyrone ring deviates from planarity and makes a dihedral angle of 8.3 (3)° with the 2-phenyl substituent. The sulfonamide group is involved in N—H⋯O hydrogen bonding.
Süheyla Özbey+3 more
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In the title molecule, C15H11NO4S, the phenyl and benzene rings are quite planar, with maximum deviations from planarity of 0.009 (2) and 0.004 (1) A, respectively. The γ-pyrone ring deviates from planarity and makes a dihedral angle of 8.3 (3)° with the 2-phenyl substituent. The sulfonamide group is involved in N—H⋯O hydrogen bonding.
Süheyla Özbey+3 more
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Difluoromethylation of Sulfonamides.
ChemInform, 2003AbstractFor Abstract see ChemInform Abstract in Full Text.
K. I. Petko+2 more
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Angewandte Chemie, 2018
Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in ...
Xiaohu Zhao+3 more
semanticscholar +1 more source
Asymmetric reductive amination of poorly nucleophilic sulfonamides was realized in the presence of nickel catalysts and titanium alkoxide. A wide range of ketones, including enolizable ketones and some biaryl ones, were converted into sulfonamides in ...
Xiaohu Zhao+3 more
semanticscholar +1 more source
Metal-free construction of primary sulfonamides through three diverse salts
, 2018In this report, the first metal-free construction of primary sulfonamides through a direct three-component reaction of sodium metabisulfite, sodium azide and aryldiazonium has been established. Readily available inorganic Na2S2O5 and NaN3 were applied as
Ming Wang+3 more
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Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15
Science, 2017Ting Han+8 more
semanticscholar +1 more source
Living with sulfonamides: a diverse range of mechanisms observed in bacteria
Applied Microbiology and Biotechnology, 2020O. Nunes+3 more
semanticscholar +1 more source