Results 1 to 10 of about 46,253 (290)
Pharmacy (Basel, Switzerland), 2019 As one of the earliest developed antimicrobial classes, sulfonamides remain important therapeutic options for the empiric and definitive treatment of various infectious diseases.
Giuseppe Gumina
exaly +6 more sources
A novel sulfonamide resistance mechanism by two-component flavin-dependent monooxygenase system in sulfonamide-degrading actinobacteria [PDF]
Environment International, 2019 Sulfonamide-degrading bacteria have been discovered in various environments, suggesting the presence of novel resistance mechanisms via drug inactivation. In this study, Microbacterium sp.
Dae-Wi Kim +2 more
exaly +4 more sources
Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues
JACS Au, 2023 Sulfonamides are one of the most important pharmacophores in medicinal chemistry, and sulfonamide analogues have gained substantial interest in recent years. However, the protein interactions of sulfonamides and especially of their analogues are underexplored.
Patrick L. Purder +9 more
core +6 more sources
A Comparative Study on the Interaction of Sulfonamide and Nanosulfonamide with Human Serum Albumin [PDF]
Journal of Chemistry, 2013 Binding parameters of the N-phenyl benzene sulfonyl hydrazide, sulfonamide, and nanosulfonamide interaction with human serum albumin were determined by calorimetry method.
G. Rezaei Behbehani +3 more
doaj +2 more sources
Guangdong nongye kexue, 2022 【Objective】With the rapid development of large-scale livestock and poultry breeding industry, the pollution of sulfonamide antibiotics in livestock and poultry manure is becoming more and more prominent.
Weida YU +6 more
doaj +1 more source
Synthesis and Characterization of Sulfonamide-Containing Naphthalimides as Fluorescent Probes
MoleculesA tumor-targeting fluorescent probe has attracted increasing interest in fluorescent imaging for the noninvasive detection of cancers in recent years. Sulfonamide-containing naphthalimide derivatives (SN-2NI, SD-NI) were synthesized by the incorporation ...
Zhi-Wei Liu +4 more
doaj +2 more sources
Sulfonamide−Pyridine-N-oxide Cocrystals
, 2016 Hydrogen-bond motifs for the supramolecular synthesis of sulfonamide−pyridine-N-oxide complexes were derived from the analysis of cocrystal structures of aryl sulfonamides and pyridine-N-oxides.
N. Rajesh Goud (1395406) +2 more
core +7 more sources
Recent Updates on the Synthesis of Bioactive Quinoxaline-Containing Sulfonamides
Applied Sciences, 2021 Quinoxaline is a privileged pharmacophore that has broad-spectrum applications in the fields of medicine, pharmacology and pharmaceutics. Similarly, the sulfonamide moiety is of considerable interest in medicinal chemistry, as it exhibits a wide range of
Ali Irfan +7 more
doaj +1 more source
, 2022 Selective glucocorticoid receptor modulators (SGRMs), which can dissociate the transactivation from the transrepression of the glucocorticoid receptor (GR), are regarded as very promising therapeutics for inflammatory and autoimmune diseases.
Lei Xu (78676) +11 more
core +2 more sources
Biomolecules, 2022 Most neurodegenerative diseases are multifactorial, and the discovery of several molecular mechanisms related to their pathogenesis is constantly advancing.
Thayssa Tavares da Silva Cunha +7 more
doaj +1 more source