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Cancer is a disease that has spread widely throughout the world and requires the development of new anticancer drugs. Curing cancer is a complicated process as the drugs that are used target human cells and cells that have undergone genetic changes and ...
Beata Żołnowska +2 more
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Supramolecular synthon hierarchy in sulfonamide cocrystals with syn-amides and N-oxides
Sulfonamide drugs are well known antibacterial and antimicrobial molecules for pharmaceutical development. Building a library of suitable supramolecular synthons for the sulfonamide functional group and understanding their crystal structures with partner
Geetha Bolla, Ashwini Nangia
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Sulfonamides and trimethoprim [PDF]
Sulfonamides and trimethoprim are inexpensive and effective antibacterial drugs that have been used extensively. The use of sulfonamides for systemic use has, however, decreased dramatically for several years, mainly because of resistance development in pathogenic bacteria and allergic side effects. Also the clinical efficiency of trimethoprim has been
openaire +2 more sources
Molecular construction of sulfonamide antisense oligonucleotides [PDF]
An efficient and scalable synthesis of new oligonucleotide monomers was developed for replacement of the phosphodiester backbone of RNA by a sulfonamide containing backbone to enable construction of novel sulfonamide antisense oligonucleotides (SaASOs ...
Korotkovs, Valerijs +5 more
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Analytical Detection of Sulfonamides and Organophosphorus Insecticide Residues in Fish in Taiwan
Exposure to residues of antibiotics (e.g., sulfonamides) and insecticides (e.g., organophosphorus insecticides) in aquacultured food can adversely affect humans and animals and thus affect public health globally.
Chung-Pei Chang +10 more
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Hydrochlorothiazide Sensitised Acetazolamide induced Bilateral Angle Closure Glaucoma with Choroidal Detachment after Cataract Surgery [PDF]
Sulfonamide (Sulfa) derived medications causing bilateral secondary angle closure glaucoma with choroidal effusion is a known but rare clinical entity.
Chitaranjan Mishra +4 more
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Coumarin compounds have a variety of biological activities such as anti-tumor, anti-coagulation, anti-HIV, anti-fungal, and insecticidal. Amide and sulfonamide compounds have been used as fungicides for half a century, and dozens of varieties have been ...
Shu-Guang Zhang +3 more
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Point Mutations in the folP Gene Partly Explain Sulfonamide Resistance of Streptococcus mutans
Cotrimoxazole inhibits dhfr and dhps and reportedly selects for drug resistance in pathogens. Here, Streptococcus mutans isolates were obtained from saliva of HIV/AIDS patients taking cotrimoxazole prophylaxis in Uganda.
W. Buwembo +4 more
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Aminoacyl sulfonamide assembly in SB-203208 biosynthesis
Sulfonamide is in many important drugs yet is rare in nature and little is known about the synthesis of sulfonamide containing antibiotics. Here, the authors report on a detailed analysis of the biosynthesis machineries of the aminoacyl sulfonamide ...
Zhijuan Hu +3 more
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Escherichia coli sinh enzyme beta-lactamases phổ rộng (ESBL-E. coli) là loài vi khuẩn gây nhiều bệnh nguy hiểm cho người và những loài động vật trên cạn. Một số nghiên cứu đã ghi nhận ESBL-E. coli xuất hiện trên cá nuôi và cá tự nhiên, điều đáng quan tâm
Phan Như Ý, Trần Thị Tuyết Hoa
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