Results 31 to 40 of about 46,253 (290)

Is Blood a Good Indicator for Detecting Antimicrobials in Meat? Evidence for the Development of In Vivo Surveillance Methods

open access: yesAntibiotics, 2020
The introduction of antimicrobial residues in the food chain has a significant impact on human health. An innovative solution to avoid their presence in meat is the adaptation of current control methods for use with in vivo matrixes. Thus, the aim was to
María Jesús Serrano   +11 more
doaj   +1 more source

Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products [PDF]

open access: yesPeerJ, 2015
This article examined the biological removal of high concentrated sulfamethazine (SMZ) antibiotics by the acclimatized activated sludge in lab-scale SBRs system.
Na Yang   +3 more
doaj   +2 more sources

A Practical and Robust Multistep Continuous Process for Manufacturing 5‑Bromo‑N‑(tert-butyl)pyridine-3-sulfonamide

open access: yes, 2019
A multistep continuous flow process involving (1) magnesium–halogen exchange, (2) sulfonylation with sulfuryl chloride, and (3) reaction with tert-butylamine was developed for the synthesis of an arylsulfonamide pharmaceutical intermediate in the ...
Scott A. Savage (2136019)   +4 more
core   +1 more source

Sulfonamide as Photoinduced Hydrogen Atom Transfer Catalyst for Organophotoredox Hydrosilylation and Hydrogermylation of Activated Alkenes

open access: yes, 2022
Readily available, sterically, and electronically tunable sulfonamides have been developed as effective photoinduced hydrogen atom-transfer (HAT) catalysts for selective Si−H functionalizations of a broad range of silanes.
Kalu Ram, Bajya   +3 more
core   +1 more source

Water‐Compatible SuFEx‐Active Diazonium Linchpin Platform for Rapid Modular Diversification and On‐DNA Functionalization

open access: yesAdvanced Functional Materials, EarlyView.
Sulfur fluoride exchange (SuFEx) is a powerful click platform, yet water‐compatible multifunctional linchpins remain elusive. Here, we report decagram‐scalable diazonium linchpins that enable rapid Pd‐catalyzed diversification and direct, catalyst‐free on‐DNA ligation in aqueous media.
Seok Ju Hong   +5 more
wiley   +1 more source

Antibacterial Residue Excretion via Urine as an Indicator for Therapeutical Treatment Choice and Farm Waste Treatment

open access: yesAntibiotics, 2021
Many of the infectious diseases that affect livestock have bacteria as etiological agents. Thus, therapy is based on antimicrobials that leave the animal’s tissues mainly via urine, reaching the environment through slurry and waste water.
María Jesús Serrano   +10 more
doaj   +1 more source

Transient Laser‐Shocked Synthesis of Amorphous Layer‐Supported Metal Nanocrystals for Efficient Nitrate Reduction

open access: yesAdvanced Materials, EarlyView.
A general, versatile laser‐shock synthesis process is reported to produce various bimetallic CuNi, CuFe, CuCo, and medium‐entropy CuFeCoNi heterostructures, in which crystalline metal nanoparticles are anchored to amorphous hydroxide supports. During nitrate reduction reaction, the heterostructures undergo dynamic amorphous/crystalline reconstruction ...
Weihua Guo   +18 more
wiley   +1 more source

Substrate‐Affinitive P‐Type Azapolycyclic Photosensitizer for Chemoselective Nitrilization Under Mild Conditions

open access: yesAdvanced Science, EarlyView.
We developed a series of quinoxalinoquinoxaline (QQ) photosensitizers featuring high and tunable excited‐state reduction potentials (E(PC•+/PC*) = –1.76 to –2.05 V vs. SCE). Their hydrogen‐bonding interaction with carbonyl substrates enables selective single‐electron transfer events for selective nitrilization of 1° amides, offering a tunable ...
Seongwoo Bae, Dongwook Kim, Jinwoo Kim
wiley   +1 more source

Covalent Reprogramming of Kinase Binders to Modulate Protein Abundance

open access: yesAdvanced Science, EarlyView.
Electrophilic remodeling of a broad‐spectrum kinase binder reveals how subtle chemical changes reprogram protein fate. An acrylamide analog of a multi‐kinase binder selectively stabilizes Aurora kinase A (AURKA) by suppressing its ubiquitination, while a short‐linker variant converts this stabilizer into a degrader.
Chen Mozes   +4 more
wiley   +1 more source

Coumarin sulfonamide derivatives: An emerging class of therapeutic agents

open access: yesHeterocyclic Communications, 2020
Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif which is a core and integral part of different therapeutic scaffolds and analogues.
Irfan Ali   +7 more
doaj   +1 more source

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