Results 261 to 270 of about 110,887 (393)

Derivatives of MOPS: promising scaffolds for SARS coronaviruses Macro domain‐targeted inhibition

open access: yesThe FEBS Journal, EarlyView.
The SARS‐CoV/CoV‐2 genome encodes non‐structural protein 3, which contains a ‘Macro domain’. This protein domain exhibits antagonistic activity against interferon signaling, which disrupts the host innate immune response and can thus mediate viral escape, highlighting its therapeutic potential.
Oney Ortega Granda   +5 more
wiley   +1 more source

Lewis Acid-Catalyzed Sulfur Fluoride Exchange. [PDF]

open access: yesOrg Lett
Yassa TD   +5 more
europepmc   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Assessing antibiotic residue presence in Turkey meat: insights from a four-box method analysis. [PDF]

open access: yesBMC Microbiol
Jaber H   +7 more
europepmc   +1 more source

Impact of sulfonamide allergy label on clinical outcomes of acute cystitis: a retrospective matched cohort study

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Cystitis is a common infection in an otherwise healthy individual. Sulfonamide antibiotics are first‐line treatment options. Sulfonamide allergy label (SAL) is the second most common antibiotic allergy label in electronic health records, yet its impact on clinical outcomes in patients with cystitis is not well‐characterised.
Ray Moussa   +3 more
wiley   +1 more source

Allosteric modulation and direct activation of glycine receptors by a tricyclic sulfonamide. [PDF]

open access: yesSci Rep
Lara CO   +17 more
europepmc   +1 more source

Catalytic insertion of nitrenes into B-H bonds. [PDF]

open access: yesChem Sci
Ankudinov NM   +5 more
europepmc   +1 more source

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