Results 71 to 80 of about 76,467 (269)

Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes.

Journal of the American Chemical Society, 2019
Single electron reduction is more challenging for sulfamoyl chlorides than sulfonyl chlorides. However, sulfamoyl and sulfonyl chlorides can be easily activated by Cl-atom abstrac-tion by a silyl radical with similar rates. This later mode of acti-vation
Sandrine M. Hell, Claudio F. Meyer, G. Laudadio, Antonio Misale, M. Willis, T. Noël, A. Trabanco, V. Gouverneur   +7 more
semanticscholar   +1 more source

Comparison of Electrochemical Immunosensors and Aptasensors for Detection of Small Organic Molecules in Environment, Food Safety, Clinical and Public Security

Biosensors, 2016
We review here the most frequently reported targets among the electrochemical immunosensors and aptasensors: antibiotics, bisphenol A, cocaine, ochratoxin A and estradiol.
Benoit Piro, Shihui Shi, Steeve Reisberg, Vincent Noël, Guillaume Anquetin   +4 more
doaj   +1 more source

Dual targeting of cancer-related human matrix metalloproteinases and carbonic anhydrases by chiral N-(biarylsulfonyl)-phosphonic acids

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
A series of nanomolar phosphonate matrix metalloproteinase (MPP) inhibitors was tested for inhibitory activity against a panel of selected human carbonic anhydrase (CA, EC 4.2.1.1) isozymes, covering the cancer-associated CA IX and XII.
Grazia Luisi, Guido Angelini, Carla Gasbarri, Antonio Laghezza, Mariangela Agamennone, Fulvio Loiodice, Claudiu T. Supuran, Cristina Campestre, Paolo Tortorella   +8 more
doaj   +1 more source

DEVELOPMENT AND VALIDATION OF A SIMPLE AND FAST METHOD FOR SULFONAMIDES, TETRACYCLINES AND MACROLIDES IN HONEY USING LC-MS/MS

Drug Analytical Research, 2018
Antibacterial are widely used in veterinary applications for diseases treatment and prophilatic purposes. Inadequate uses of these drugs can lead of undesirable residues in honey for consumption.
Cristina Belissimo Ribeiro, Magda Targa Martins, Louise Jank, Fabiano Barreto, Rodrigo Barcellos Hoff , Juliana Bazzan Arsand   +5 more
doaj   +1 more source

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

Animal Research and One Health, EarlyView.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista, Lucas dos Santos Janotto, Adriana Paula Possamai, Carolina Cini Perry, Francine Lemes Ribeiro, Rafael Canonenco de Araujo, Fernando Bittencourt Luciano   +6 more
wiley   +1 more source

A randomized, pilot trial comparing full versus escalating dose regimens for the desensitization of AIDS patients allergic to sulfonamides

Brazilian Journal of Infectious Diseases
Sulfonamides are drugs extensively used in the management of AIDS patients. However, the use of sulfonamides is often associated with the development of allergic reactions, provoking the substitution of the drug (by another that may be less effective ...
Andrea Straatmann, Fabianna Bahia, Diana Pedral-Sampaio, Carlos Brites   +3 more
doaj   +1 more source

Kinase Inhibitors that Increase the Sensitivity of Methicillin Resistant Staphylococcus aureus to β-Lactam Antibiotics

Pathogens, 2015
Staphylococcus aureus are Gram-positive bacteria that are the leading cause of recurrent infections in humans that include pneumonia, bacteremia, osteomyelitis, arthritis, endocarditis, and toxic shock syndrome.
Jay Vornhagen, Kellie Burnside, Christopher Whidbey, Jessica Berry, Xuan Qin, Lakshmi Rajagopal   +5 more
doaj   +1 more source

NHC-Catalyzed Deamination of Primary Sulfonamides: A Platform for Late-Stage Functionalization.

Journal of the American Chemical Society, 2019
Herein we describe the development and application of a method for the mild, late-stage conversion of primary sulfonamides to several other other functional groups. These reactions occur via initial reductive deamination of sulfonamides to sulfinates via
P. Fier, K. Maloney
semanticscholar   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Removal of nutrients from water column and physiological responses of Vallisneria natans under sulfonamide stress

Journal of Freshwater Ecology, 2019
For a better understanding of the metabolic adaptations to sulfonamide (SA) stress in submerged macrophytes, the alterations of nutrient element uptake and secondary metabolism were studied in the leaves of Vallisneria natans (Lour.) Hara exposed to 0 ...
Houtao Xu, Liming Zhu, Liqing Wang, Xiaoyan Zheng, Linkui Cao   +4 more
doaj   +1 more source