Results 71 to 80 of about 113,455 (289)

Special Issue: Sulfonamides [PDF]

open access: yesMolecules, 2017
The sulfonamides and their structurally related derivatives, such as the sulfamates and sulfamides, possess the general formula A-SO2NHR, in which the functional group is either directly bound to an aromatic, heterocyclic, aliphatic, or sugar scaffold (of type A), or appended to such a scaffold via a heteroatom, most frequently oxygen or nitrogen ...
openaire   +4 more sources

Antibiotics in Raw Meat Samples: Estimation of Dietary Exposure and Risk Assessment

open access: yesToxics, 2022
The extensive use of antibiotics in livestock farming poses increased concerns for human health as residues of these substances are present in edible tissues.
Athina Stavroulaki   +11 more
doaj   +1 more source

NHC-Catalyzed Deamination of Primary Sulfonamides: A Platform for Late-Stage Functionalization.

open access: yesJournal of the American Chemical Society, 2019
Herein we describe the development and application of a method for the mild, late-stage conversion of primary sulfonamides to several other other functional groups. These reactions occur via initial reductive deamination of sulfonamides to sulfinates via
P. Fier, K. Maloney
semanticscholar   +1 more source

A REVIEW ON SULFONAMIDES

open access: yes, 2020
Sulfonamide drugs were the first antimicrobial drugs. The first sulfonamide was trade named Prontosil, which is a prodrug Prontosil, the first commercially available antibacterial with a relatively broad effect The sulphonamides or sulfa drugs competitively inhibit folic acid synthesis in micro-organisms and subsequently inhibit multiplication of ...
Mr.Visal C.S   +4 more
openaire   +3 more sources

Determination of Pharmaceuticals in Coastal Systems Using Solid Phase Extraction (SPE) Followed by Ultra Performance Liquid Chromatography – tandem Mass Spectrometry (UPLC-MS/MS) [PDF]

open access: yes, 2015
This paper describes the optimization and validation of an analytical method for the determination of 83 pharmaceutically active compounds (PhACs) in aqueous samples using solid-phase extraction (SPE) followed by ultra performance liquid chromatography ...
Baena Nogueras, Rosa María   +3 more
core   +1 more source

Otimização e validação de método multirresíduo para determinação de sulfonamidas em camarão cultivado por cromatografia líquida de alta eficiência com detecção por UV

open access: yesQuímica Nova, 2011
This work reports the optimization and method validation for sulfonamides (sulfamethazine, sulfaquinoxaline, sulfadimethoxine and sulfathiazole) in shrimp muscle using HPLC-UV.
Paloma Nascimento dos Santos   +4 more
doaj   +1 more source

New Cu+2 Complexes with N-Sulfonamide Ligands: Potential Antitumor, Antibacterial, and Antioxidant Agents

open access: yesMolecules, 2022
Nowadays, the discovery of a new non-toxic metal complex with biological activity represents a very active area of research. Two Cu+2 complexes, [Cu(L1)2(H2O)3] (C1) (HL1= N-(5-(4-methylphenyl)-[1,3,4]–thiadiazole–2-yl)-naphtalenesulfonamide) and [Cu(L2 ...
Adriana Corina Hangan   +6 more
doaj   +1 more source

Practical access to axially chiral sulfonamides and biaryl amino phenols via organocatalytic atroposelective N-alkylation

open access: yesNature Communications, 2019
The importance of axial chirality in enantioselective synthesis has been widely recognized for decades. The practical access to certain structures such as biaryl amino phenols known as NOBINs in enantiopure form, however, still remains a challenge.
Shenci Lu   +7 more
semanticscholar   +1 more source

New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
A series of organometallic acylhydrazones was prepared, incorporating Re(CO)3, Mn(CO)3 and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in order to obtain carbonic anhydrase (CA, EC 4.2.1.1) inhibitors possessing ...
Yosselin Huentupil   +5 more
doaj   +1 more source

Enantioselective Radical Construction of 5-Membered Cyclic Sulfonamides by Metalloradical C-H Amination.

open access: yesJournal of the American Chemical Society, 2019
Both arylsulfonyl and alkylsulfonyl azides can be effectively activated by the cobalt(II) complexes of D2-symmetric chiral amidoporphyrins for enantioselective radical 1,5-C-H amination to stereoselectively construct 5-membered cyclic sulfonamides.
Yang Hu   +11 more
semanticscholar   +1 more source

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