Results 141 to 150 of about 7,119 (254)

One-Pot Morita-Baylis-Hillman/Allylic Substitution in Deep Eutectic Solvents: Access to γ-Hydroxy Derivatives via Sequential CC and CX (X = P, N, S, B, Si) Bond Formation. [PDF]

ChemSusChem
Ramos-Martín M, Del Río I, García-Álvarez J, Presa Soto A.   +3 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Modular synthesis of CF₂-containing compounds with PhSO₂CF₂H reagent through difluoromethylene radical anion synthon strategy. [PDF]

Nat Commun
Sun S, Jia R, Zhou X, Wang Z, Rong J, Ni C, Hu J.   +6 more
europepmc   +1 more source

SULFONATION [PDF]

Chemical & Engineering News Archive, 1998
openaire   +1 more source

The plasticisation model of dye diffusion: Part 8

Coloration Technology, EarlyView.
Abstract Re‐evaluation using the Williams–Landel–Ferry equation, of exhaustion/rate of dyeing/fixation data previously reported for and acid dye, natural dye and two reactive dyes on three different types of silk substrate revealed that thermally activated dye diffusivity is governed by the thermally regulated structural relaxation times of the ...
Stephen M. Burkinshaw
wiley   +1 more source

Discovery of Fluorotelomer Sulfones in the Blubber of Greenland Killer Whales (<i>Orcinus orca</i>). [PDF]

Environ Sci Technol Lett
Lauria MZ, Shi X, Haque F, Plassmann M, Roos A, Simon M, Benskin JP, Jobst KJ.   +7 more
europepmc   +1 more source

Four Haylages, One Metabonome: Defining Diet Driven Metabolic Shifts in Ponies

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Haylage is widely fed to all categories of stabled horses across Europe and New Zealand. Haylage can vary from high energy nutrient dense forage to low energy highly fibrous fodder, yet little is known about the impact different haylages have on metabolism in horses.
Meriel Moore‐Colyer, Pat Harris, Simon Daniels   +2 more
wiley   +1 more source

Modular, Tricomponent, and Concurrent One-Pot Synthesis of Libraries of γ-Keto Sulfones and γ-Keto Phosphine Oxides using Brønsted Acidic Eutectic Mixtures. [PDF]

ChemSusChem
Ramos-Martín M, García-Álvarez J, Presa Soto A.   +2 more
europepmc   +1 more source

Plasma Pharmacokinetic Profile of Fipronil 1% Pour‐On in Cattle: Photodegradation and the Sustained Systemic Persistence of Fipronil Sulfone

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This study characterized the long‐term pharmacokinetic profile of a 1% fipronil pour‐on formulation in Nellore bulls under field conditions. Seventeen animals received a single topical dose (1 mg/kg), and plasma concentrations of fipronil and its metabolites (sulfone and desulfinyl) were monitored for 175 days using LC–MS/MS.
Stefani Maria Ferreira, Leonila Ester Reinert Raspantini, Giselle Kindlein, Fabiano Barreto, Caroline Andrade Tomaszewski, Tamara dos Santos Castilhos, Daniel Rodrigo Hillesheim, Silvana Lima Górniak, André Tadeu Gotardo   +8 more
wiley   +1 more source

Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-controlled photoreactor. [PDF]

Chem Sci
Wang S, Le QT, Shishido Y, Kokculer IY, Yamazaki K, Perry GJP, Nightingale AM, Yorimitsu H.   +7 more
europepmc   +1 more source