Results 161 to 170 of about 21,252 (299)

Memory of Chirality in Radical Addition–Translocation–Cyclization Cascades

Helvetica Chimica Acta, EarlyView.
Radical addition–translocation–cyclization cascades of chiral alkynes show striking memory of chirality (MoC), with strong retention of configuration when fast, polarity favored cyclization are involved. The most effective system employs a highly electron‐poor pentafluorobenzenesulfonyl group.
Christian Simon Gloor, Fabrice Dénès, Valentin Soulard, Philippe Renaud   +3 more
wiley   +1 more source

Photochemical Synthesis of Ynones from Aryl Aldehydes and Sulfone-Based Alkynes. [PDF]

J Org Chem
Cruise A, Baumann M.
europepmc   +1 more source

Response to Oral Dapsone in a Patient With Generalised Junctional Epidermolysis Bullosa

JEADV Clinical Practice, EarlyView.
ABSTRACT Dapsone is a potent antibacterial agent used as a first‐line treatment for leprosy and employed also as an anti‐inflammatory agent. Additionally, dapsone is used for a variety of other cutaneous conditions. Herein, we report a case of intermediate junctional epidermolysis bullosa that improved significantly with oral 4,4’‐diamino‐diphenyl ...
Shiho Mori, Manabu Fujimoto, Katsuto Tamai   +2 more
wiley   +1 more source

Microwave-assisted single-step synthesis of cyclic and acyclic β-aminosulfones and evaluation of their antifungal activity targeting CYP51. [PDF]

RSC Med Chem
Pinheiro AB, Saha S, Madduri M, Roy U, Menon LS, Biswas S, Chatterjee A, Banerjee M.   +7 more
europepmc   +1 more source

Metathesis‐Sourced Epoxides in Ring‐Opening Copolymerization: Selective Access to Degradable Polythioesters

Macromolecular Rapid Communications, EarlyView.
Metathesis‐derived cyclopentene epoxides enable strictly alternating, scrambling‐free ring‐opening copolymerization with phthalic thioanhydride, yielding well‐defined polythioesters with molecular weights up to ∼38 kg/mol. Their performance extends to oxygen‐based anhydrides and selective terpolymerizations. Direct comparisons with all‐oxygen analogues
Niracha Tangyen, Bhargav R. Manjunatha, Valerio D'Elia, Alex J. Plajer   +3 more
wiley   +1 more source

Formation of cyclopentanes and cyclopropanes through alkylation of benzylic anions using ethers, thioethers and alcohols as substrates under Grubbs-Stoltz (Et₃SiH/KO<i>t</i>Bu) conditions. [PDF]

Chem Sci
Stewart AJ, Dimitrova D, Logan STM, Pratley C, Bell JD, McGonigal K, Lauer A, Fenner S, Nicolle SM, Leach SG, Murphy JA.   +10 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

A Three-Layer Transformation Strategy toward Functionalized Fused Hydantoins and Diketopiperazines. [PDF]

Org Lett
Giannakaki MA, Zingiridis M, Froudas KG, Neochoritis CG.   +3 more
europepmc   +1 more source

Electrospun conducting polymers: recent trends and the transition towards a sustainable future

Polymer International, EarlyView.
This review discusses the electrospinning of conducting polymers, detailing procedures, fibrous morphologies, improved properties, applications in electronics, and challenges, while outlining future directions for nanofibre‐based devices in various fields.
Xenofon Karagiorgis, Sofia Sandhu, Peter J. Skabara, Ravinder Dahiya   +3 more
wiley   +1 more source

Visible-Light-Mediated Radical Truce-Smiles Rearrangement via Arylazo Sulfones. [PDF]

JACS Au
Di Terlizzi L, Nicchio L, Montinho-Inacio E, Tiwari N, Derat E, Retailleau P, Fagnoni M, Neuville L, Protti S, Masson G.   +9 more
europepmc   +1 more source