Results 181 to 190 of about 12,336 (293)

Sulfur fluoride exchange with carbon pronucleophiles. [PDF]

open access: yesChem Sci
Novicki JR   +6 more
europepmc   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur   +6 more
wiley   +1 more source

Pyridine-boryl radical mediated synthesis of quinolines <i>via</i> α-amino radical formation and intramolecular alkenyl sulfone trapping.

open access: yesOrg Chem Front
Valderrama-Callejón R   +7 more
europepmc   +1 more source

Electroreductive Desulfurization of Thioacetals

open access: yesChemElectroChem, Volume 13, Issue 12, 17 June 2026.
A metal‐free electrochemical protocol enabled desulfurization of thioacetals under ambient conditions. Aryl substituents on sulfur act as internal electroauxiliaries to promote C(sp3)─S bond cleavage via a radical pathway, effectively serving as alternative to the Mozingo reduction.
Ellymay Goossens   +7 more
wiley   +1 more source

MnCl2‐Catalyzed Photochemical Functionalization of Unactivated C(sp3)H Bonds

open access: yesChemSusChem, Volume 19, Issue 11, 15 June 2026.
A photochemical method enables the activation of alkanes, utilizing cheap and abundant MnCl2 as the photocatalyst. Alkenylation and alkylation reactions are performed, affording the desired products in good yields. Activation of inert C(sp3)H bonds is of great importance in organic synthesis, since it can functionalize unreactive molecules, such as ...
Naya A. Stini   +3 more
wiley   +1 more source

Discovery of Fluorotelomer Sulfones in the Blubber of Greenland Killer Whales (<i>Orcinus orca</i>). [PDF]

open access: yesEnviron Sci Technol Lett
Lauria MZ   +7 more
europepmc   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Tunable Aromatic Sulfoxides and Sulfones as Cysteine-Targeting Warheads: Exploring the Structure-Reactivity Relationship. [PDF]

open access: yesJ Med Chem
Nyström H   +8 more
europepmc   +1 more source

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