ABSTRACT This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...
T. Zuberbier +221 more
wiley +1 more source
Synthesis, Functionalization, and Reactivity of Vinyl Sulfondiimidamides
Combining unsymmetrical sulfurdiimide reagents (R‐NSN‐R1) and Grignard reagents, followed by oxidative amination, delivers a series of vinyl sulfondiimidamides. Reactivity with cysteine and lysine derivatives is shown, and the cysteine reactivity is mapped in detail. Variation of the two imidic N‐substituents can be used to tune reactivity of these new
Katherine G. Rodden +4 more
wiley +2 more sources
Photoredox catalysed reductive cleavage of dibenzothiophene dioxides enabled by a temperature-controlled photoreactor. [PDF]
Wang S +7 more
europepmc +1 more source
Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown +2 more
wiley +1 more source
Arylazo Sulfones as 1,3-Dipole Acceptors in the (Photo)-Micellar van Leusen Triazole Synthesis. [PDF]
Volpe C +11 more
europepmc +1 more source
The plasticisation model of dye diffusion: Part 8
Abstract Re‐evaluation using the Williams–Landel–Ferry equation, of exhaustion/rate of dyeing/fixation data previously reported for and acid dye, natural dye and two reactive dyes on three different types of silk substrate revealed that thermally activated dye diffusivity is governed by the thermally regulated structural relaxation times of the ...
Stephen M. Burkinshaw
wiley +1 more source
Modular, Tricomponent, and Concurrent One-Pot Synthesis of Libraries of γ-Keto Sulfones and γ-Keto Phosphine Oxides using Brønsted Acidic Eutectic Mixtures. [PDF]
Ramos-Martín M +2 more
europepmc +1 more source
Synthesis of (E)‐β‐SF5‐Styrenes via a Heck Reaction of in situ Generated Vinylsulfur Pentafluoride†
A Heck cross‐coupling reaction between aryl(hetero)iodides and in situ generated vinylsulfur pentafluoride is reported. This reaction provides β‐SF5‐styrenes in one‐step as a single (E)‐stereoisomer and tolerates a broad range of functional groups. Comprehensive Summary The synthesis of (E)‐(1‐alken‐1‐yl)pentafluoro‐λ6‐sulfanes, a valuable class of ...
Nicolas DeGrâce +1 more
wiley +1 more source
Electrochemical Sulfonylation in Deep Eutectic Solvents Enables the Sustainable Synthesis of 2-Quinoline Sulfones. [PDF]
Adsuar D +3 more
europepmc +1 more source

