Results 71 to 80 of about 24,524 (277)

Long‐term follow‐up of children with in utero exposure to sulfonylurea medications

open access: yes, 2021
Background Offspring born to mothers with gestational diabetes mellitus (GDM) are more likely to have negative neurodevelopmental health outcomes, early obesity, type 2 diabetes, and metabolic syndrome in childhood, adolescence, and adulthood.
Rodenstein, Marissa S   +11 more
core   +2 more sources

Recent Advances in Neonatal Diabetes

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Amanda Dahl, Seema Kumar Division of Pediatric Endocrinology and Metabolism, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USACorrespondence: Seema KumarDivision of Pediatric Endocrinology and Metabolism, Department of ...
Dahl A, Kumar S
doaj  

From ions to insulin

open access: yeseLife, 2017
Electron cryo-microscopy has revealed the three-dimensional structure of a potassium channel that has a central role in regulating the release of insulin from the pancreas.
Voula Kanelis
doaj   +1 more source

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi   +9 more
wiley   +1 more source

Sulfonylurea drugs increase early mortality in patients with diabetes mellitus after direct angioplasty for acute myocardial infarction

open access: yes, 1999
Objectives. The purpose of this study was to examine the impact of sulfonylurea drug use on outcome in diabetic patients undergoing direct coronary angioplasty for acute myocardial infarction.Background. Sulfonylurea drugs impair ischemic preconditioning.
David R Holmes   +11 more
core   +1 more source

Secular Trend in Glycaemic Management in Type 2 Diabetes Patients With and Without Cirrhosis Between 2000 and 2023: A Territory‐Wide Cohort Study

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In this territory‐wide cohort study, improving glycemic control can be observed regardless of cirrhosis status. Oral antidiabetic medication was more often used in the non‐cirrhosis group, and insulin was preferred in patients with decompensated cirrhosis, who exhibited an increasing incidence of hypoglycemia over the years and need individualized ...
Mary Yue Wang   +6 more
wiley   +1 more source

Mechanism of KATP hyperactivity and sulfonylurea tolerance due to a diabetogenic mutation in L0 helix of sulfonylurea receptor 1 (ABCC8)

open access: yes, 2011
Activating mutations in different domains of the ABCC8 gene-coded sulfonylurea receptor 1 (SUR1) cause neonatal diabetes. Here we show that a diabetogenic mutation in an unexplored helix preceding the ABC core of SUR1 dramatically increases open ...
Vaxillaire, Martine   +3 more
core   +1 more source

TIVMETIX OD – A Sulfonylurea-based Herbicide with improved efficacy through novel oil dispersion (OD) formulation technology

open access: yesJulius-Kühn-Archiv, 2016
TIVMETIX OD is a novel oil dispersion (OD) post-emergence herbicide for the spring application (BBCH 13-39) against broad-leafed weeds in all varieties of winter and spring wheat, winter and spring barley, winter rye and triticale.
Gimeno, Barbara   +4 more
doaj   +1 more source

Expert considerations to guide the development and delivery of an exercise intervention in people with type 2 diabetes‐related foot ulcer disease

open access: yesDiabetic Medicine, EarlyView.
Abstract Objective Engaging in exercise presents unique challenges for those with type 2 diabetes (T2D) and diabetes‐related foot ulcer disease (DFUD). This brief report describes the development of practical considerations aiming to support exercise in people with T2D and DFUD.
Vicki L. Johnson   +17 more
wiley   +1 more source

Sulfonylurea-insensitive permanent neonatal diabetes caused by a severe gain-of-function Tyr330His substitution in Kir6.2

open access: yes, 2022
Background/aims: Mutations in KCNJ11, the gene encoding the Kir6.2 subunit of pancreatic and neuronal KATP channels, are associated with a spectrum of neonatal diabetes diseases. Methods: Variant screening was used to identify cause of neonatal diabetes,
Perri, Alessandro   +14 more
core   +1 more source

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