Results 21 to 30 of about 20,495 (161)

Effect of genetic polymorphisms on the development of secondary failure to sulfonylurea in Egyptian patients with type 2 diabetes

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2011
Objective: This study investigated the possibility that genetic factors, such as polymorphism of K inward rectifier subunit (Kir6.2), E23K, and Arg 972 polymorphism of insulin receptor substrate-1 (IRS-1), may predispose patients to sulfonylurea failure.
Alaa E. El-sisi   +4 more
doaj   +1 more source

Severe nephrotic syndrome and early end-stage diabetic kidney disease in ABCC8-MODY12: A case report

open access: yesFrontiers in Genetics, 2023
A 24-year-old man with diabetes mellitus presented with advanced kidney disease and severe proteinuria. Genetic testing revealed ABCC8-MODY12 (OMIM 600509), and a kidney biopsy showed nodular glomerulosclerosis.
Sophie H. Schmidt   +9 more
doaj   +1 more source

Assessing the environmental risks of sulfonylurea pollutants: Insights into the risk priority and structure-toxicity relationships

open access: yesEcotoxicology and Environmental Safety
Sulfonylureas are widely used herbicides globally; however, the health risks associated with exposure to these compounds are poorly understood. This study used fuzzy clustering to categorize 44 sulfonylurea compounds into three risk priority levels (I ...
Zhi-Cong He   +5 more
doaj   +1 more source

Efeitos da adubação nitrogenada em cobertura sobre a seletividade de herbicidas à cultura do milho Effects of cover nitrogen fertilization on herbicide selectivity in corn

open access: yesPlanta Daninha, 2006
O objetivo deste trabalho foi avaliar os efeitos da adubação nitrogenada de cobertura sobre a seletividade dos herbicidas aplicados em pós-emergência na cultura do milho (Zea mays). Para isso, foram conduzidos dois experimentos.
M. Nicolai   +4 more
doaj   +1 more source

A Prospective Observational Study to Compare the Efficacy and Adverse Effects of Glimepiride and Vildagliptin Added to Metformin in Type 2 Diabetes Mellitus [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2019
Introduction: In order to prevent the specific diabetes mellitus related macrovascular and microvascular complications, guidelines by American Diabetes Association recommend a reasonable glycosylated haemoglobin goal for non-pregnant adults to be less ...
Biswanath Sharma Sarkar   +3 more
doaj   +1 more source

Assessment of methyl 2-({[(4,6-dimethoxypyrimidin-2-yl)carbamoyl] sulfamoyl}methyl)benzoate through biotic and abiotic degradation modes

open access: yesOpen Chemistry, 2020
Detoxification and management of environmental contaminants is an exigent issue of current times. Sulfonylurea herbicide, Bensulfuron-methyl was investigated for its degradation demeanour in soils, through biotic and abiotic modes (biodegradation and ...
Gul Mahwash Mahar, Ahmad Khuram Shahzad
doaj   +1 more source

Sulfonylureas at the Glomerular Battlefield [PDF]

open access: yesEuropean Endocrinology, 2018
The kidney is important in the context of diabetes not only because it is involved in normal glucose homeostasis, but also because it is one of the most important end organs to be involved in diabetes complications. Glomeruli are the meeting point of both microvascular, or renal; and macrovascular, or cardiovascular, health in diabetes.
Kalra, Sanjay   +3 more
openaire   +2 more sources

Comparison of the effectiveness of different oral glucose lowering drugs in fasting patients with type II diabetes [PDF]

open access: yesInternational Journal of Biomedicine and Public Health, 2018
Introduction: Type 2 diabetes is the most common metabolic diseases in developed and developing countries with no effective treatment options. This study purpose was to compare different regimens of oral anti-diabetic therapy effects on the type 2 ...
Mernoosh Zakerkish   +4 more
doaj   +1 more source

Inheritance and molecular characterization of resistance to AHAS-inhibiting herbicides in rapeseed

open access: yesJournal of Integrative Agriculture, 2017
Rapeseed is a very important oil crop in China; however, its production is challenging due to the absence of effective weed management strategies. This is predominantly because of a shortage of herbicide resistance genes. Acetohydroxyacid synthase (AHAS)
Mao-long HU   +9 more
doaj   +1 more source

Metformin-Insulin versus Metformin-Sulfonylurea Combination Therapies in Type 2 Diabetes: A Comparative Study of Glycemic Control and Risk of Cardiovascular Diseases in Addis Ababa, Ethiopia

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2021
Desye Gebrie,1,2 Tsegahun Manyazewal,2 Dawit A Ejigu,3 Eyasu Makonnen2,4 1School of Pharmacy, College of Health Sciences, Mekelle University, Mekelle, Ethiopia; 2Center for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa ...
Gebrie D   +3 more
doaj  

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