Results 221 to 230 of about 1,582,904 (250)

Kinetic Compatibility as a Predictor of PTP1B Inhibitor Combination Outcomes: An Integrated Experimental and Computational Study

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Combining PTP1B inhibitors of distinct kinetic mechanisms determines their pharmacological outcome. Integrating enzyme kinetics, docking, molecular dynamics, and membrane‐permeability simulations, we show that mechanistically compatible pairs (competitive + competitive; uncompetitive + mixed) yield additivity, whereas competitive + uncompetitive ...
Jonathan Trapala   +7 more
wiley   +1 more source

Stacked mutations in multi-copy AHAS genes enhance sulfonylurea herbicide resistance in soybean. [PDF]

open access: yesPlant J
Park K   +11 more
europepmc   +1 more source

Engineering Herbicide Cross‐Resistance in Rapeseed by Generating Stacked BnaALS Mutations via Sequential CBE and ABE8e‐SpRY Editing

open access: yes
Plant Biotechnology Journal, Volume 24, Issue 9, Page 5007-5009, September 2026.
Sichao Ren   +10 more
wiley   +1 more source

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