Reduction of Sulfonylurea with the Initiation of Basal Insulin in Patients with Inadequately Controlled Type 2 Diabetes Mellitus Undergoing Long-Term Sulfonylurea-Based Treatment [PDF]
, 2016 BackgroundThere were a limited number of studies about β-cell function after insulin initiation in patients exposed to long durations of sulfonylurea treatment.
Jeong-Ah Shin +7 more
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CHIMIA, 2004 The introduction of fluorine atoms into 2-phenyl-4H-3,1-benzoxazin-4-one (bentranil) led to sweeping changes in its herbicidal properties in some cases, and 5-fluoro-2-phenyl-4H-3,1-benzoxazin-4-one ('fluorobentranil') was found to be the most ...
Gerhard Hamprecht +2 more
doaj +1 more source
Monitoring the Occurrence of Sulfonylurea-Resistant Prickly Lettuce (Lactuca serriola)
, 1992 Sulfonylurea herbicide-resistant prickly lettuce was discovered in Idaho in 1987. The objectives of these surveys were to determine the change with time in the proportion of sulfonylurea resistant and susceptible prickly lettuce biotypes on the farm ...
Carol Mallory-Smith +2 more
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Frontiers in Microbiology, 2015 Gut microbiota has recently been proposed as a crucial environmental factor in the development of metabolic diseases such as obesity and type 2 diabetes, mainly due to its contribution in the modulation of several processes including host energy ...
Magali ePalau-Rodriguez +6 more
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A disrupter of actin microfilaments impairs sulfonylurea-inhibitory gating of cardiac KATP channels
, 1996 The efficacy with which sulfonylurea drugs inhibit cardiac ATP-sensitive K+ (KATP) channels is reduced during metabolic compromise and cellular contracture.
P. A. Brady +4 more
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Differential interaction of glimepiride and glibenclamide with the β-cell sulfonylurea receptor II [PDF]
, 1994 Glimepiride is a novel sulfonylurea for the treatment of type II-diabetic patients exhibiting different receptor binding kinetics to β-cell membranes with 8–9-fold higher koff rate and 2.5–3-fold higher kon rate compared to glibenclamide (see ...
Kramer, Werner +13 more
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The sulfonylurea receptor Sur is dispensable for chitin synthesis in Drosophila melanogaster embryos
, 2013 Background: Chitin produced by membrane-inserted chitin synthases is an important constituent of the arthropod cuticle and midgut peritrophic matrix. Chitin synthesis inhibitors are common insecticides in pest control.
Meyer, F. +2 more
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SEPARATION OF SULFONYLUREA METABOLITES IN WATER BY CAPILLARY ELECTROPHORESIS
, 1995 The potential of capillary electrophoresis (CE) for the separation and detection of the metabolites of nine sulfonylurea herbicides in aqueous solution was evaluated.
VICARI A, BONETTI A, DINELLI G
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Recent Developments in Diabetes Management: Exploring Receptors, Pathways, and Compounds
BIO IntegrationDiabetes mellitus (DM) is a widespread metabolic disorder with profound effects on vital organs. Often referred to as a “systemic” or “multi-organ” disorder due to the impact on key organs, such as the kidneys, pancreas, eyes, and heart, DM is ...
Pallavi Pandey +3 more
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Hepatic sensitivity to insulin: effects of sulfonylurea drugs
, 1991 Insulin regulation of hepatic glucose production (HGP) is altered in non-insulin-dependent diabetes mellitus (NIDDM), resulting in increased glucose output by the liver; this contributes to the elevation in plasma glucose concentration observed both in ...
Vigili de Kreutzenberg S +3 more
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