Results 11 to 20 of about 5,240 (162)

Efficacy and Safety of Pioglitazone versus Glimepiride after Metformin and Alogliptin Combination Therapy: A Randomized, Open-Label, Multicenter, Parallel-Controlled Study [PDF]

open access: yesDiabetes & Metabolism Journal, 2020
BackgroundThere is limited information regarding the optimal third-line therapy for managing type 2 diabetes mellitus (T2DM) that is inadequately controlled using dual combination therapy.
Jeong Mi Kim   +12 more
doaj   +1 more source

The clinical aspects ot the sulphonylurea compounds from the position of the cardioprotective approach at patient with type 2 diabetes, using glucocardiomonitoring

open access: yesСахарный диабет, 2022
BACKGRAUND: Now the trend of Type 2 Diabetes Mellitus (T2DM) management from glucocentric to cardioprotective approach take place, and it especially relevant for the multiple group of patients with T2DM using Sulphonylurea (SU).
N. A. Chernikova   +3 more
doaj   +1 more source

Bioequivalence assessment of the two brands of glimepiride tablets [PDF]

open access: yesVojnosanitetski Pregled, 2006
Background/Aim. Glimepiride, as an antidiabetic from the group of sulfonylurea, is administered perorally in the treatment of diabetes mellitus. The aim of this study was to compare pharmacokinetic profiles and relative bioavailabilities of the two oral ...
Jovanović Dušan   +4 more
doaj   +1 more source

Correction to: “Cardiovascular Outcomes Comparison of Dipeptidyl Peptidase-4 Inhibitors Versus Sulfonylurea as Add-on Therapy for Type 2 Diabetes Mellitus: A Meta-Analysis”

open access: yesJournal of Lipid and Atherosclerosis, 2022
Objective Recent studies have raised concerns about the cardiovascular safety of dipeptidyl peptidase-4 (DPP4) inhibitors. We performed a systematic review and meta-analysis to compare the cardiovascular outcomes of sulfonylureas (SUs) versus DPP4 ...
Won Kyeong Jeon   +3 more
doaj   +1 more source

Additional Effect of Dietary Fiber in Patients with Type 2 Diabetes Mellitus Using Metformin and Sulfonylurea: An Open-Label, Pilot Trial [PDF]

open access: yesDiabetes & Metabolism Journal, 2019
BackgroundMetformin, sulfonylurea, and dietary fiber are known to affect gut microbiota in patients with type 2 diabetes mellitus (T2DM). This open and single-arm pilot trial investigated the effects of the additional use of fiber on glycemic parameters,
Seung-Eun Lee   +7 more
doaj   +1 more source

Cardiovascular Outcomes Comparison of Dipeptidyl Peptidase-4 Inhibitors versus Sulfonylurea as Add-on Therapy for Type 2 Diabetes Mellitus: a Meta-Analysis

open access: yesJournal of Lipid and Atherosclerosis, 2021
Objective Recent studies have raised concern about the cardiovascular safety of dipeptidyl peptidase-4 (DPP4) inhibitors. We performed a systematic review through meta-analysis to compare cardiovascular outcomes of sulfonylurea (SU) versus DPP4 ...
Won Kyeong Jeon   +3 more
doaj   +1 more source

Alkaline Soil Degradation and Crop Safety of 5-Substituted Chlorsulfuron Derivatives

open access: yesMolecules, 2022
Sulfonylurea herbicides can lead to serious weed resistance due to their long degradation times and large-scale applications. This is especially true for chlorsulfuron, a widely used acetolactate synthase inhibitor used around the world.
Lei Wu   +5 more
doaj   +1 more source

Design, Synthesis and in Vivo Evaluation of Novel Glycosylated Sulfonylureas as Antihyperglycemic Agents

open access: yesMolecules, 2015
Sulphonylurea compounds have versatile activities such as antidiabetic, diuretic, herbicide, oncolytic, antimalarial, antifungal and anticancer. The present study describes the design, synthesis and in vivo testing of novel glycosylated aryl sulfonylurea
Ghadeer A. R. Y. Suaifan   +4 more
doaj   +1 more source

Solvent-Free Synthesis and Safener Activity of Sulfonylurea Benzothiazolines

open access: yesMolecules, 2017
A series of novel sulfonylurea benzothiazolines was designed by splicing active groups and bioisosterism. A solvent-free synthetic route was developed for the sulfonylurea benzothiazoline derivatives via the cyclization and carbamylation.
Ying Fu   +6 more
doaj   +1 more source

Novel Sulfonylurea Derivatives as Potential Antimicrobial Agents: Chemical Synthesis, Biological Evaluation, and Computational Study

open access: yesAntibiotics, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) is a worldwide health threat and has already tormented humanity during its long history, creating an urgent need for the development of new classes of antibacterial agents.
Fan-Fei Meng   +8 more
doaj   +1 more source

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