Results 71 to 80 of about 1,671,881 (203)

Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis

open access: yes, 2010
Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(═O)NHMe to understand the conformational and tautomeric preferences.
Kasetti, Yoganjaneyulu   +11 more
core   +2 more sources

Study on the effect of electrochemical treatment of nicosulfuron wastewater

open access: yesMATEC Web of Conferences, 2018
Nicosulfuron, a kind of sulfonylurea herbicide, because of its high activity and low dosage, has been widely used in corn planting weeding. Electrochemical method was chosen to treat its simulated waste water and the influence factors such as current ...
Zhao Rui, Jiang Wenqiang
doaj   +1 more source

Sulfonylurea induced beta-cell apoptosis in cultured human islets

open access: yes, 2005
Loss of beta-cell mass and function raises a concern regarding the application of sulfonylureas for the treatment of type 2 diabetes because previous studies have shown that agents that cause closure of inwardly rectifying K(+) sulfonylurea receptor ...
Carr, Richard D   +5 more
core   +1 more source

Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin [PDF]

open access: yes, 2014
Three series of novel sulfonylurea podophyllotoxin derivatives were designed, synthesized, and evaluated for in vitro cytotoxicity against four tumor cell lines (A-549, DU-145, KB and KBvin). Compounds 14c (IC50: 1.41–1.76 μM) and 14e (IC50: 1.72–2.01 μM)
Wang, Mei Juan   +8 more
core   +1 more source

Response of maize (Zea mays L.) to rimsulfuron under salt conditions

open access: yesActa Societatis Botanicorum Poloniae, 2011
Investigations were carried out to determine the possible interaction between salinity (60 mmol*dm-3 NaCl) and phytotoxicity of herbicide Titus 25 DF (sulfonylurea herbicide containing active ingredient rimsulfuron).
Elżbieta Sacała   +2 more
doaj   +1 more source

Sulfonylurea-induced hypoglycaemia: use of octreotide.

open access: yes, 2009
Sulfonylurea compounds are commonly used to treat type 2 diabetes mellitus. The case of an old alcoholic addicted diabetic patient treated with gliquidone developing recurrent and prolonged hypoglycaemias refractory to dextrose administration is related.
Hanchard, B   +2 more
core  

New type of Sulfonylureas as an AHAS enzyme inhibitor: Calculation in Molecular Docking

open access: yes, 2021
It is aimed to substitute the pyrimidinone group instead of the pyrimidine group in sulfonylurea herbicides sold in the market. Because, according to the literature data (and patents received), the pyrimidinone group shows herbicidal activity. Our aim is
Canbolat, Nüveyre, Karacan, Nurcan
core   +1 more source

Cytochrome P450 2C9*2 and *3 polymorphisms and the dose and effect of sulfonylurea in type II diabetes mellitus

open access: yes, 2008
Sulfonylurea hypoglycemics are mainly metabolized by the cytochrome P450 2C9 ( CYP2C9) enzyme. The CYP2C9*2 and *3 polymorphisms encode proteins with less enzymatic activity and are correlated with elevated serum levels of sulfonylurea, as demonstrated ...
Stricker, Bruno   +5 more
core   +1 more source

Signaling and sites of interaction for RX-871024 and sulfonylurea in the stimulation of insulin release

open access: yes, 1998
The objective of this study was to compare effects of RX-871024, a compound with imidazoline structure, and the sulfonylurea glibenclamide, representatives of two groups of ATP-dependent potassium channel (KATP) blockers, on insulin secretion and ...
Berggren, PO   +20 more
core   +1 more source

Sulfonylurea herbicides

open access: yes, 1991
Available from British Library Document Supply Centre- DSC:q91/15871(Sulfonylurea) / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Smith, C   +1 more
core  

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