Results 71 to 80 of about 1,671,881 (203)
Conformational Polymorphism in Sulfonylurea Drugs: Electronic Structure Analysis
Quantum chemical calculations have been performed using HF, B3LYP, and MP2 methods on the model sulfonylurea PhSO2NHC(═O)NHMe to understand the conformational and tautomeric preferences.
Kasetti, Yoganjaneyulu +11 more
core +2 more sources
Study on the effect of electrochemical treatment of nicosulfuron wastewater
Nicosulfuron, a kind of sulfonylurea herbicide, because of its high activity and low dosage, has been widely used in corn planting weeding. Electrochemical method was chosen to treat its simulated waste water and the influence factors such as current ...
Zhao Rui, Jiang Wenqiang
doaj +1 more source
Sulfonylurea induced beta-cell apoptosis in cultured human islets
Loss of beta-cell mass and function raises a concern regarding the application of sulfonylureas for the treatment of type 2 diabetes because previous studies have shown that agents that cause closure of inwardly rectifying K(+) sulfonylurea receptor ...
Carr, Richard D +5 more
core +1 more source
Design, synthesis and cytotoxic activity of novel sulfonylurea derivatives of podophyllotoxin [PDF]
Three series of novel sulfonylurea podophyllotoxin derivatives were designed, synthesized, and evaluated for in vitro cytotoxicity against four tumor cell lines (A-549, DU-145, KB and KBvin). Compounds 14c (IC50: 1.41–1.76 μM) and 14e (IC50: 1.72–2.01 μM)
Wang, Mei Juan +8 more
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Response of maize (Zea mays L.) to rimsulfuron under salt conditions
Investigations were carried out to determine the possible interaction between salinity (60 mmol*dm-3 NaCl) and phytotoxicity of herbicide Titus 25 DF (sulfonylurea herbicide containing active ingredient rimsulfuron).
Elżbieta Sacała +2 more
doaj +1 more source
Sulfonylurea-induced hypoglycaemia: use of octreotide.
Sulfonylurea compounds are commonly used to treat type 2 diabetes mellitus. The case of an old alcoholic addicted diabetic patient treated with gliquidone developing recurrent and prolonged hypoglycaemias refractory to dextrose administration is related.
Hanchard, B +2 more
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New type of Sulfonylureas as an AHAS enzyme inhibitor: Calculation in Molecular Docking
It is aimed to substitute the pyrimidinone group instead of the pyrimidine group in sulfonylurea herbicides sold in the market. Because, according to the literature data (and patents received), the pyrimidinone group shows herbicidal activity. Our aim is
Canbolat, Nüveyre, Karacan, Nurcan
core +1 more source
Sulfonylurea hypoglycemics are mainly metabolized by the cytochrome P450 2C9 ( CYP2C9) enzyme. The CYP2C9*2 and *3 polymorphisms encode proteins with less enzymatic activity and are correlated with elevated serum levels of sulfonylurea, as demonstrated ...
Stricker, Bruno +5 more
core +1 more source
The objective of this study was to compare effects of RX-871024, a compound with imidazoline structure, and the sulfonylurea glibenclamide, representatives of two groups of ATP-dependent potassium channel (KATP) blockers, on insulin secretion and ...
Berggren, PO +20 more
core +1 more source
Available from British Library Document Supply Centre- DSC:q91/15871(Sulfonylurea) / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Smith, C +1 more
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