Results 241 to 250 of about 293,753 (306)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Metabolic engineering of <i>Saccharomyces cerevisiae</i> for co-production of ergothioneine, salidroside and gadusol. [PDF]

Synth Syst Biotechnol
Zhang L, Xiao S, Wang D, Zhang P, Xu R, Hu L, Kang Z.   +6 more
europepmc   +1 more source

Effects of Autophagy Inhibition by SAR405, a Selective VPS34 Inhibitor, on Pleural Mesothelioma Cells. [PDF]

Thorac Cancer
Kuwabara Y, Sakai K, Shiraishi K, Matsumoto I, Ishii S, Yokosuka S, Abe M, Takahashi T, Kawano Y, Nishimura H, Toda-Sasaki M, Kobayashi-Ogawa Y, Kikuchi S, Hirata Y, Kyoyama H, Moriyama G, Koyama N, Uematsu K.   +17 more
europepmc   +1 more source

Comprehensive chemical, morphological, thermal, and biological characterization of Agave tequilana extract and chitosan-based dissolving microneedle arrays. [PDF]

PLoS One
Quintero-Rincón P, Caballero-Gallardo K, Flórez-Acosta O.   +2 more
europepmc   +1 more source

Comparison between the crystal structures of racemic and enantiopure aryl benzyl sulfoxides. [PDF]

RSC Adv
Capozzi MAM, Alvarez-Larena A, Piniella Febrer JF, Cardellicchio C.   +3 more
europepmc   +1 more source

Upregulation of Sox2 Following Saracatinib Treatment Contributes to a Resistant Phenotype in Colorectal Cancer Cells under Growth Factor-Supplemented Conditions. [PDF]

Oncol Res
Yoon C, Na E, Choi MJ, Yoon SP.
europepmc   +1 more source

Impact of Thymidine Loop Modifications on Telomeric G-Quadruplex Catalytic Systems for Asymmetric Sulfoxidation. [PDF]

Molecules
Finamore C, Festa C, Benigno D, Aliberti C, Barbato R, De Marino S, Galeone A, Esposito V, Virgilio A.   +8 more
europepmc   +1 more source