Results 21 to 30 of about 267,790 (260)

pH-Dependence of the Aqueous Phase Room Temperature Brønsted Acid-Catalyzed Chemoselective Oxidation of Sulfides with H2O2

open access: yesMolecules, 2015
A pH-dependence of the Brønsted acid-catalyzed oxidation of sulfides to the corresponding sulfoxides with H2O2 is reported for the first time based on our systematic investigation of the catalytic performance of a series of Brønsted acids. For all of the
Hai-Min Shen   +8 more
doaj   +1 more source

Thiol-free chemoenzymatic synthesis of β-ketosulfides

open access: yesBeilstein Journal of Organic Chemistry, 2019
A preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipase-catalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor.
Adrián A. Heredia   +4 more
doaj   +1 more source

Synthesis and Evaluation of Novel Benzofuran Derivatives as Selective SIRT2 Inhibitors

open access: yesMolecules, 2017
A series of benzofuran derivatives were designed and synthesized, and their inhibitory activites were measured against the SIRT1–3. The enzymatic assay showed that all the compounds showed certain anti-SIRT2 activity and selective over SIRT1 and SIRT3 ...
Yumei Zhou   +10 more
doaj   +1 more source

Ndufaf2, a protein in mitochondrial complex I, interacts in vivo with methionine sulfoxide reductases

open access: yesRedox Report, 2023
Background Methionine sulfoxide reductases are found in all aerobic organisms. They function in antioxidant defense, cellular regulation by reversible oxidation of methionine in proteins, and in protein structure.
Sujin Park   +2 more
doaj   +1 more source

Factors associated with variation in single-dose albendazole pharmacokinetics: A systematic review and modelling analysis.

open access: yesPLoS Neglected Tropical Diseases, 2022
BackgroundAlbendazole is an orally administered anti-parasitic medication with widespread usage in a variety of both programmatic and clinical contexts.
Charles Whittaker   +6 more
doaj   +1 more source

Sulfoxides

open access: yes, 2014
Citation: 'sulfoxides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.S06124 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
null Anna, George Wypych
openaire   +2 more sources

Crosstalk of TNF-α, IFN-γ, NF-kB, STAT1 and redox signaling in lipopolysaccharide/d-galactosamine/dimethylsulfoxide-induced fulminant hepatic failure in mice

open access: yesSaudi Pharmaceutical Journal, 2023
Purpose: The clinical study of fulminant hepatic failure is challenging due to its high mortality and relative rarity, necessitating reliance on pre-clinical models to gain insight into its pathophysiology and develop potential therapies.
Abdulrazaq Alanazi   +10 more
doaj   +1 more source

Crystal structures of polymerized lithium chloride and dimethyl sulfoxide in the form of {2LiCl·3DMSO}n and {LiCl·DMSO}n

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2023
Two novel LiCl·DMSO polymer structures were created by combining dry LiCl salt with dimethyl sulfoxide (DMSO), namely, catena-poly[[chloridolithium(I)]-μ-(dimethyl sulfoxide)-κ2O:O-[chloridolithium(I)]-di-μ-(dimethyl sulfoxide)-κ4O:O], [Li2Cl2(C2H6OS)3]n,
Nichole R. Valdez   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Racemic-Benzimidazolyl Pentafluorobenzyl Sulfoxide

open access: yesMolbank
As a part of our research on the presence of conglomerates among the aryl benzyl sulfoxides, racemic-benzimidazolyl pentafluorobenzyl sulfoxide was synthesised, and its crystal structure was determined by a single crystal X-ray diffraction experiment ...
Maria Annunziata M. Capozzi   +1 more
doaj   +1 more source

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