Results 131 to 140 of about 43,014 (276)

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

Reconstructing Redox Landscape With Coupled Nitrogen‐Sulfur Isotopes: A Case Study From Middle‐Late Triassic Chang 7 Member of the Yanchang Formation in the Ordos Basin (North China)

Geochemistry, Geophysics, Geosystems
Euxinia, a crucial geological condition, usually signifies more severe extinction events attributed to deoxygenation in Earth's history. Despite extensive exploration of various proxies in paleoredox studies, most are primarily utilized to reconstruct ...
Xubin Wang, Lin Dong, Tong Li, Kun Ling, Changhu Zhang, Yijie Bin, Ziyi Wang, Zhijun Jin, Jinhua Fu   +8 more
doaj   +1 more source

Effect of ammonium concentration on methane oxidation and CO2 removal in an anaerobic biotrickling filter treating synthetic landfill gas and leachate

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Landfill gas (LFG) and leachate are commonly treated separately through energy‐intensive processes. This study evaluated the integration of both streams in an anaerobic biotrickling filter (BTF) to achieve simultaneous methane (CH4) and carbon dioxide (CO2) removal coupled with ammonium (NH4+) transformation, and how the microbial ...
Cecilia Lizeth Alvarez‐Guzmán, Karla María Muñoz‐Páez, Alejandro Vargas, Idania Valdez‐Vazquez   +3 more
wiley   +1 more source

The relation between isotopic composition of argon and carbon in natural gases [PDF]

The methods and results of determination of the argon and carbon isotope compositions of hydrocarbon gases of Mezozoic complexes of Western Siberia are presented.
Gavrilov, Y. Y., Teplinskiy, G. I., Zhurov, Y. A.   +2 more
core   +1 more source

Liebig Review: Essential and Beneficial Elements in the Regulation of Cadmium Uptake and Tolerance in Crop Plants

Journal of Plant Nutrition and Soil Science, EarlyView.
ABSTRACT Cadmium (Cd2+) contamination in agricultural soils has been reported to pose risks to crop productivity, food safety, and human health. This review synthesizes current knowledge on the mechanisms by which essential (S, Zn, Fe, Mg, K, Ca) and beneficial (Si, Se, rare earth elements) elements mitigate Cd2+ toxicity in plants.
Maria Manzoor, Karl Hermann Mühling
wiley   +1 more source

Snapshots of Coastal Ecology Using Multiproxy Analysis Reveals Insights Into the Preservation of Swamp and Marsh Environments Since the Late Pleistocene

Geochemistry, Geophysics, Geosystems
The southeastern United States Coastal Plain ecosystem contains baldcypress (Taxodium distichum) swamps and grass‐dominated marshes. These ecosystems also occurred on the exposed continental shelf during lower sea levels but are rarely preserved due to ...
Kendall Fontenot, Kristine L. DeLong, Brian A. Schubert, Sophie Warny, Davin J. Wallace, Carrie M. Miller, Erin Culver‐Miller, Michael J. Polito, Carl A. Reese, Kathryn Garretson, Kehui Xu, Grant L. Harley, Jeffrey Obelcz, Kelli L. Moran, Julian Traphagan, Douglas Jones, Alicia Caporaso   +16 more
doaj   +1 more source

Deglaciation of the Burren glacio‐karst, western Ireland, during Termination 1: Implications for North Atlantic climate and karstification

Journal of Quaternary Science, EarlyView.
Abstract The Burren uplands in western Ireland form one of the most extensive and best‐preserved examples of glacio‐karst in Europe. Subsumed by the Irish ice sheet during the Late Pleistocene, granite erratic boulders and in situ silica veins in the limestone bedrock provide a rare opportunity to reconstruct the timing and rate of deglaciation ...
Gordon Bromley, Colin Bunce, Brenda Hall, Aaron Putnam, Frank McDermott   +4 more
wiley   +1 more source

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt, Adriana Arigò, Giorgio Famiglini, Pierangela Palma, Achille Cappiello   +4 more
wiley   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Microbially driven organic carbon cycling at the land−sea interface: Advances and an integrated study framework

mLife, EarlyView.
Abstract The land−sea interface is a vital component of global biogeochemical cycles, where microorganisms drive the cycling of carbon, nitrogen, and sulfur. This review synthesizes the research progress from representative land−sea interfaces to elucidate how the microbial community structure and metabolic function influence the mobilization ...
Quanrui Chen, Kai Tang, Zhili He, Meng Li, Jun Yang, Weidong Zhai, Qiang Zheng, Nianzhi Jiao   +7 more
wiley   +1 more source