Results 51 to 60 of about 74,360 (259)

Biocompatibility and Long‐Term Stability of DNA‐Based Organic Mixed Conductors for Bioelectronics

Advanced Materials Interfaces, EarlyView.
The biocompatibility and long‐term stability of DNA‐based mixed ionic‐electronic conductors are investigated. In vitro cytotoxicity and cell viability are assessed using flow cytometry assay on primary mouse fibroblasts cultures. The biocomposites are integrated into organic electrochemical transistors (OECTs) to determine the stability of their ...
Sarka Hradilova, Katharina Matura, Munise Cobet, Ariana Opletalova, Yolanda Salinas, Niyazi Serdar Sariciftci, Serpil Tekoglu, Katerina Polakova   +7 more
wiley   +1 more source

Cysteine Metabolism and Oxidative Processes in the Rat Liver and Kidney after Acute and Repeated Cocaine Treatment. [PDF]

PLoS ONE, 2016
The role of cocaine in modulating the metabolism of sulfur-containing compounds in the peripheral tissues is poorly understood. In the present study we addressed the question about the effects of acute and repeated (5 days) cocaine (10 mg/kg i.p ...
Danuta Kowalczyk-Pachel, Małgorzata Iciek, Karolina Wydra, Ewa Nowak, Magdalena Górny, Małgorzata Filip, Lidia Włodek, Elżbieta Lorenc-Koci   +7 more
doaj   +1 more source

Solvent‐ and Transition Metal‐Free Mechanochemical Synthesis of 2‐Thiazolines and S‐Thiocarbamates

Advanced Synthesis &Catalysis, EarlyView.
Solvent‐ and transition metal‐free synthetic pathways for obtaining 2‐thiazolines and S‐thiocarbamates, based on the mechanochemical process of addition of chloroalkyl iso(thio)cyanates to thiols catalyzed by cheap and commercially available K2CO3, are designed and optimized.
Kamil Hanek, Natalia Pietras, Dawid Frąckowiak, Patrycja Żak   +3 more
wiley   +1 more source

On‐Chip Multiplexed Voltammetry Using a Universal Antifouling Hydrogel and Porous Gold Foam Interface for Stress and Inflammation Monitoring

Advanced Sensor Research, EarlyView.
A multiplexed device is fabricated via silicon microelectronics and adapted for electrochemical sensing interface. Its 100 um gold disk electrodes are modified with porous gold foam and coated with a rapid, biocompatibleantifouling layer. Universal immunoglobulin G (IgG) capture is enabled through Protein A/G.
Vuslat B. Juska, Stacey Hendriks, Esmeralda Santillan‐Urquiza, Nadia Moukri, Pedro Estrela, Graeme D. Maxwell, Bernadette O'Brien, Bernardo Patella, Rosalinda Inguanta, Alan O'Riordan   +9 more
wiley   +1 more source

Intrinsically Soft Implantable Electronics for Long‐term Biosensing Applications

Advanced Sensor Research, EarlyView.
Intrinsically soft implantable biosensors address the mechanical mismatch of conventional rigid implants, improving biocompatibility and stability. This review explores soft encapsulation matrices, stretchable conductors, implantation strategies, and chronic fixation techniques.
Su Hyeon Lee, Hyo Jin Lee, Sohye Lee, Dae‐Hyeong Kim, Hye Jin Kim, Sung‐Hyuk Sunwoo   +5 more
wiley   +1 more source

Cost‐Effective Hierarchical Cobalt Nanostructured Laser‐Induced Graphene for Enhanced Uric Acid Detection

Advanced Sensor Research, EarlyView.
A one‐step electrochemical strategy is utilized to develop a flexible, enzyme‐free biosensor for the sensitive detection of uric acid (UA). The hierarchical cobalt nanostructures synergistically enhance the performance of the biosensor, resulting in a broad detection range of 5 to 700 µM with a sensitivity of 6.75 µA µM−1 cm−2 and a low detection limit
Anju Joshi, Gymama Slaughter
wiley   +1 more source

Selective Co‐Assembly of Water‐Soluble Conjugated Polyelectrolyte with Discernable Fluorescence Modulation for Antibiotic Detection

Advanced Sensor Research, EarlyView.
PQx‐Ph, a water‐soluble conjugated polyelectrolyte, enables rapid and selective fluorescence‐based detection of structurally distinct antibiotics via supramolecular assembly modulation. It achieves nanomolar sensitivity under mild conditions and preserves reliable sensing performance across NOM‐rich and biologically relevant water matrices, supporting ...
Hyena Ji, Yesica Fernanda Florez‐Villabona, Youngsun Kim, Yerim Kim, Yongju Kim, Seungyun Baik, Young Hun Seo, Sehoon Kim   +7 more
wiley   +1 more source

Disintegration of the KITENIN/ErbB4 Functional Complex by the Flavonoid Hispidulin Suppresses Colorectal Cancer Progression

Advanced Therapeutics, EarlyView.
Hispidulin disrupts the KITENIN/ErbB4 oncogenic complex and inhibits KITENIN‐mediated AP‐1 activity, cell invasion, and aerobic glycolysis. It also suppresses the production of cancer‐associated metabolites and downregulates transcriptional regulators downstream of the KITENIN complex.
Mücahit Varlı, Songjin Oh, Eunae Kim, Barış Gökalsın, Nüzhet Cenk Sesal, Kyung Keun Kim, Man Jeong Paik, Hangun Kim   +7 more
wiley   +1 more source

Self‐Adjusting Engineered Probiotic for Targeted Tumor Colonization and Local Therapeutics Delivery

Advanced Science, EarlyView.
Zou et al. developed an engineered strain of Escherichia coli Nissle 1917 with precise targeting abilities for colonization and on‐demand payload release. The engineered probiotic survives and embolizes tumors only in the presence of more than 5 mM L‐lactate. Furthermore, the introduction of an α‐hemolysin circuit enhances its anti‐tumor effect.
Zhen‐Ping Zou, Xin‐Ge Wang, Xuan‐Ren Shi, Shu‐Ting Sun, Jing Mi, Xiao‐Peng Zhang, Bin‐Cheng Yin, Ying Zhou, Bang‐Ce Ye   +8 more
wiley   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source